Cutoff values of protein induced by vitamin K absence or antagonist II for diagnosing hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000030936
Abstract: Protein induced by vitamin K absence or antagonist II (PIVKA-II) is a promising serum marker for hepatocellular carcinoma (HCC). There are limited data on its cutoff value in HCC for Taiwanese cirrhosis patients. This study… read more here.
Keywords: vitamin absence; pivka; cutoff; absence antagonist ... See more keywords
Value of AFP and PIVKA-II in diagnosis of HBV-related hepatocellular carcinoma and prediction of vascular invasion and tumor differentiation
Sign Up to like & getrecommendations! Published in 2020 at "Infectious Agents and Cancer"
DOI: 10.1186/s13027-020-00337-0
Abstract: Background To explore the value of alpha fetoprotein (AFP) and protein induced by vitamin K absence or antagonist-II (PIVKA-II) in diagnosis of HBV-related hepatocellular carcinoma (HCC) and their relationship with vascular invasion, tumor differentiation and… read more here.
Keywords: vascular invasion; pivka; hbv related; afp pivka ... See more keywords
Utility of combining PIVKA-II and AFP in the surveillance and monitoring of hepatocellular carcinoma in the Asia-Pacific region
Sign Up to like & getrecommendations! Published in 2023 at "Clinical and Molecular Hepatology"
DOI: 10.3350/cmh.2022.0212
Abstract: Even though the combined use of ultrasound (US) and alpha-fetoprotein (AFP) is recommended for the surveillance of hepatocellular carcinoma (HCC), the utilization of AFP has its challenges, including accuracy dependent on its cut-off levels, degree… read more here.
Keywords: hepatocellular carcinoma; surveillance; hcc; asia pacific ... See more keywords
Progression of Prothrombin Induced by Vitamin K Absence-II in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.726213
Abstract: Hepatocellular carcinoma (HCC) is the fifth most common cancer and the third leading cause of cancer-related death worldwide. Due to the lack of efficient tools for early detection, asymptomatic HCC patients are diagnosed at an… read more here.
Keywords: induced vitamin; pivka; hepatocellular carcinoma; vitamin absence ... See more keywords
Identification of the Best Cut-Off Value of PIVKA-II for the Surveillance of Patients at Risk of Hepatocellular Carcinoma Development
Sign Up to like & getrecommendations! Published in 2023 at "Biology"
DOI: 10.3390/biology12010094
Abstract: Simple Summary The use of tumor biomarkers, although debated, for the surveillance of patients at risk of HCC, is common practice in many clinical centers. Here, we investigated the best cut-off value for one of… read more here.
Keywords: best cut; pivka; cut value; surveillance ... See more keywords
Diagnostic Performance of Extrahepatic Protein Induced by Vitamin K Absence in the Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2023 at "Diagnostics"
DOI: 10.3390/diagnostics13050816
Abstract: Background and Objectives: the early diagnosis of hepatocellular carcinoma (HCC) benefits from the use of alpha-fetoprotein (AFP) together with imaging diagnosis using abdominal ultrasonography, CT, and MRI, leading to improved early detection of HCC. A… read more here.
Keywords: vitamin absence; hepatocellular carcinoma; pivka; meta analysis ... See more keywords
Investigating a Prognostic Factor for Canine Hepatocellular Carcinoma: Analysis of Different Histological Grading Systems and the Role of PIVKA-II
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Sciences"
DOI: 10.3390/vetsci9120689
Abstract: Simple Summary PIVKA-II is an aberrant form of vitamin K that is increased in human coagulation disfunctions and in some neoplastic diseases. In veterinary medicine, PIVKA-II concentrations can be useful to identify patients with coagulative… read more here.
Keywords: histological grading; hepatocellular carcinoma; canine; hcc ... See more keywords
PIVKA-II as a surrogate marker for prognosis in patients with localized hepatocellular carcinoma receiving stereotactic body radiotherapy
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DOI: 10.3857/roj.2021.00934
Abstract: Purpose This study aimed to determine the correlation between protein induced by vitamin K absence or antagonist-II (PIVKA-II) and stereotactic body radiotherapy (SBRT) in patients with hepatocellular carcinoma (HCC). Materials and Methods Sixty-one patients received… read more here.
Keywords: hepatocellular carcinoma; stereotactic body; surrogate marker; body radiotherapy ... See more keywords
Prognostic value of preoperative protein-induced vitamin K absence or antagonist II after liver resection for hepatitis B-related hepatocellular carcinoma: a nationwide multicenter study
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Surgical Treatment and Research"
DOI: 10.4174/astr.2022.103.5.271
Abstract: Purpose Although protein-induced vitamin K absence or antagonist II (PIVKA-II) has been used as a diagnostic tool for hepatocellular carcinoma (HCC), its prognostic value remains unclear. Methods This was a nationwide multicenter study using the… read more here.
Keywords: hcc specific; hepatitis related; hcc; liver resection ... See more keywords
Review on Vitamin K Deficiency and its Biomarkers: Focus on the Novel Application of PIVKA-II in Clinical Practice.
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DOI: 10.7754/clin.lab.2017.171020
Abstract: BACKGROUND Vitamin K (VK) is a co-factor of the γ-glutamyl carboxylase that catalyzes the conversion of glutamate residues to γ-carboxyglutamate in VK-dependent proteins. The carboxylation reaction imparts the essential calcium-binding residues for the biological function… read more here.
Keywords: pivka; application; review vitamin; deficiency ... See more keywords