LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "piwi interacting" as a keyword



Photo by nci from unsplash

PIWI‐interacting RNA 39980 promotes tumor progression and reduces drug sensitivity in neuroblastoma cells

Sign Up to like & get
recommendations! Published in 2019 at "Journal of Cellular Physiology"

DOI: 10.1002/jcp.29136

Abstract: Neuroblastoma (NB) is the leading pediatric cancer known for its heterogeneity and clinical aggressiveness leading to chemoresistance. Recent evidence in small RNA research has led to the discovery of PIWI‐interacting RNAs (piRNAs) which work in… read more here.

Keywords: tumor progression; piwi interacting; pir 39980; drug ... See more keywords
Photo by libraryofcongress from unsplash

PIWI-interacting RNA sequencing profiles in maternal plasma-derived exosomes reveal novel non-invasive prenatal biomarkers for the early diagnosis of nonsyndromic cleft lip and palate

Sign Up to like & get
recommendations! Published in 2021 at "EBioMedicine"

DOI: 10.1016/j.ebiom.2021.103253

Abstract: Background Congenital malformations are common birth defects with high neonatal morbidity and mortality. It is essential to find simpler and more efficient biomarkers for early prenatal diagnosis. Therefore, we investigated PIWI-interacting RNAs (piRNAs) as potential… read more here.

Keywords: piwi interacting; biomarkers early; women carrying; normal foetuses ... See more keywords
Photo by paipai90 from unsplash

Decay of Piwi-Interacting RNAs in Human Cells Is Primarily Mediated by 5' to 3' Exoribonucleases.

Sign Up to like & get
recommendations! Published in 2022 at "ACS chemical biology"

DOI: 10.1021/acschembio.2c00007

Abstract: Piwi-interacting RNAs (piRNAs) are a group of small noncoding RNA molecules that regulate the activity of transposons and control gene expression. The cellular concentration of RNAs is generally maintained by their rates of biogenesis and… read more here.

Keywords: piwi interacting; rnas human; interacting rnas; degradation ... See more keywords
Photo by polarmermaid from unsplash

Decoding the 5′ nucleotide bias of PIWI-interacting RNAs

Sign Up to like & get
recommendations! Published in 2019 at "Nature Communications"

DOI: 10.1038/s41467-019-08803-z

Abstract: PIWI-interacting RNAs (piRNAs) are at the center of a small RNA-based immune system that defends genomes against the deleterious action of mobile genetic elements (transposons). PiRNAs are highly variable in sequence with extensive targeting potential.… read more here.

Keywords: piwi interacting; bias piwi; piwi; nucleotide bias ... See more keywords
Photo by matnapo from unsplash

An introduction to PIWI-interacting RNAs (piRNAs) in the context of metazoan small RNA silencing pathways

Sign Up to like & get
recommendations! Published in 2022 at "RNA Biology"

DOI: 10.1080/15476286.2022.2132359

Abstract: ABSTRACT PIWI proteins and their associated PIWI-interacting RNAs (piRNAs) constitute a small RNA-based adaptive immune system that restricts the deleterious activity of mobile genetic elements to protect genome integrity. Self/nonself discrimination is at the very… read more here.

Keywords: piwi interacting; rna; rnas pirnas; interacting rnas ... See more keywords
Photo by paipai90 from unsplash

PIWI-interacting RNAs in human diseases: databases and computational models

Sign Up to like & get
recommendations! Published in 2022 at "Briefings in bioinformatics"

DOI: 10.1093/bib/bbac217

Abstract: PIWI-interacting RNAs (piRNAs) are short 21-35 nucleotide molecules that comprise the largest class of non-coding RNAs and found in a large diversity of species including yeast, worms, flies, plants and mammals including humans. The most… read more here.

Keywords: piwi interacting; computational models; human diseases; databases computational ... See more keywords
Photo from wikipedia

Prediction of Piwi-Interacting RNAs and Their Functions via Convolutional Neural Network

Sign Up to like & get
recommendations! Published in 2021 at "IEEE Access"

DOI: 10.1109/access.2021.3070083

Abstract: In eukaryotic cells, Piwi-interacting RNAs (piRNAs) are the type of short chain non-coding RNA molecules, which interconnect with PIWI proteins. It performs various cellular and genetic functions such as gene-specific protein translation, expression regulation, maintenance,… read more here.

Keywords: neural network; piwi interacting; interacting rnas; convolutional neural ... See more keywords
Photo by karsten116 from unsplash

Artificial "ping-pong" cascade of PIWI-interacting RNA in silkworm cells.

Sign Up to like & get
recommendations! Published in 2017 at "RNA"

DOI: 10.1261/rna.058875.116

Abstract: PIWI-interacting RNAs (piRNAs) play essential roles in the defense system against selfish elements in animal germline cells by cooperating with PIWI proteins. A subset of piRNAs is predicted to be generated via the "ping-pong" cascade,… read more here.

Keywords: piwi interacting; pong cascade; artificial ping; piwi ... See more keywords
Photo by hajjidirir from unsplash

iPiDA-LTR: Identifying piwi-interacting RNA-disease associations based on Learning to Rank

Sign Up to like & get
recommendations! Published in 2022 at "PLoS Computational Biology"

DOI: 10.1371/journal.pcbi.1010404

Abstract: Piwi-interacting RNAs (piRNAs) are regarded as drug targets and biomarkers for the diagnosis and therapy of diseases. However, biological experiments cost substantial time and resources, and the existing computational methods only focus on identifying missing… read more here.

Keywords: piwi interacting; ipida ltr; based learning; disease associations ... See more keywords
Photo by matnapo from unsplash

Knockout Gene-Based Evidence for PIWI-Interacting RNA Pathway in Mammals

Sign Up to like & get
recommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.681188

Abstract: The PIWI-interacting RNA (piRNA) pathway mainly consists of evolutionarily conserved protein factors. Intriguingly, many mutations of piRNA pathway factors lead to meiotic arrest during spermatogenesis. The majority of piRNA factor-knockout animals show arrested meiosis in… read more here.

Keywords: interacting rna; piwi interacting; knockout gene; pathway ... See more keywords
Photo from wikipedia

Emerging roles and potential application of PIWI-interacting RNA in urological tumors

Sign Up to like & get
recommendations! Published in 2023 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.1054216

Abstract: The piRNA (PIWI-interacting RNA) is P-Element induced wimpy testis (PIWI)-interacting RNA which is a small molecule, non-coding RNA with a length of 24-32nt. It was originally found in germ cells and is considered a regulator… read more here.

Keywords: piwi interacting; roles potential; interacting rna; emerging roles ... See more keywords