Novel piRNA Regulates PIWIL1 to Modulate the Behavior of Placental Trophoblast Cells and Participates in Preeclampsia
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/7856290
Abstract: Objectives This study is aimed at investigating the role of PIWIL1/piRNA in the development of preeclampsia. Methods High-throughput sequencing was performed in 5 preeclampsia and 5 normal placentas to get a piRNA expression profile. WGCNA… read more here.
Keywords: piwil1; expression; preeclampsia; trophoblast cells ... See more keywords
The Piwil1 N domain is required for germ cell survival in Atlantic salmon
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.977779
Abstract: Genetic introgression of farmed salmon into wild populations can damage the genetic integrity of wild stocks and is therefore considered as an environmental threat. One possible solution is to induce sterility in farmed salmon. We… read more here.
Keywords: germ cell; germ; piwil1; loss ... See more keywords
Meioc-Piwil1 complexes regulate rRNA transcription for differentiation of spermatogonial stem cells
Sign Up to like & getrecommendations! Published in 2025 at "eLife"
DOI: 10.7554/elife.104295
Abstract: Ribosome biogenesis is vital for sustaining stem cell properties, yet its regulatory mechanisms are obscure. Herein, we show unique properties of zebrafish meioc mutants in which spermatogonial stem cells (SSCs) do not differentiate or upregulate… read more here.
Keywords: differentiation; piwil1; stem cells; meioc ... See more keywords