PIWIL2 is overexpressed in adenomyotic lesions of women with diffuse adenomyosis
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-020-05660-w
Abstract: Purpose Adenomyosis has been studied throughout the years, however, its aetiology and physiopathology are still unknown. The aim of this study was to identify the presence of PIWI proteins in women with adenomyosis. Methods We… read more here.
Keywords: adenomyosis; overexpressed adenomyotic; lesions women; piwil2 ... See more keywords
Hypothalamic-Pituitary-Gonadal (HPG) Axis and Transcriptional Regulatory Elements Regulate piwil2 Gene Expression During Gametogenesis and Gonadal Development in Japanese Flounder (Paralichthys olivaceus)
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Ocean University of China"
DOI: 10.1007/s11802-020-4442-0
Abstract: The P-element induced wimpy testis (Piwi) proteins, which are associated with PIWI-interacting RNAs (piRNAs), play important roles in meiosis, germ cell division, and germline maintenance. In this study, we identified and characterized the Paralichthys olivaceus… read more here.
Keywords: gonadal; piwil2; paralichthys olivaceus; expression ... See more keywords
Attenuation of Piwil2 induced by hypoxic postconditioning prevents cerebral ischemic injury by inhibiting CREB2 promoter methylation
Sign Up to like & getrecommendations! Published in 2022 at "Brain Pathology"
DOI: 10.1111/bpa.13109
Abstract: Epigenetic modification contributes to the pathogenesis of cerebral ischemia. Piwil2 belongs to the PIWI proteins subfamily and has a key role in the regulation of gene transcription through epigenetics. However, the roles of Piwil2 in… read more here.
Keywords: tgci; piwil2 induced; cerebral ischemia; induced hypoxic ... See more keywords
Cancer/testis antigen PIWIL2 suppresses circadian rhythms by regulating the stability and activity of BMAL1 and CLOCK.
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DOI: 10.18632/oncotarget.18973
Abstract: Circadian rhythms are regulated by transcriptional and post-translational feedback loops generated by appropriate functions of clock proteins. Rhythmic degradation of the circadian clock proteins is critical for maintenance of the circadian oscillations. Notably, circadian clock… read more here.
Keywords: circadian rhythms; piwil2; bmal1 clock; cancer ... See more keywords
PIWIL2 Regulates the Proliferation, Apoptosis and Colony Formation of Colorectal Cancer Cell Line
Sign Up to like & getrecommendations! Published in 2023 at "Iranian Journal of Biotechnology"
DOI: 10.30498/ijb.2022.307054.3176
Abstract: Background: Tumor cells proliferation and apoptosis inhibition are the mechanisms through which the Colorectal Cancer (CRC) progression, metastasis and chemoresistance are promoted pathologically, offering clinical advantages for characterizing their molecular regulators. Objectives: In this study,… read more here.
Keywords: cell; apoptosis; proliferation; colony formation ... See more keywords
High expression of PIWIL2 promotes tumor cell proliferation, migration and predicts a poor prognosis in glioma.
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DOI: 10.3892/or.2017.5647
Abstract: Piwi-like RNA-mediated gene silencing 2 (PIWIL2), has been reported as an oncogene tightly associated with the genesis and progression of various malignancies. Nevertheless, the function of the PIWIL2 protein in human gliomas has not yet been… read more here.
Keywords: glioma; poor prognosis; piwil2; expression ... See more keywords