Regulation of PGC1α downstream of the insulin signaling pathway plays a role in the hepatic proteotoxicity of mutant α1-antitrypsin deficiency variant Z.
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology"
DOI: 10.1053/j.gastro.2022.03.010
Abstract: BACKGROUND AND AIMS Insulin signaling is known to regulate essential proteostasis mechanisms. METHODS The analyses here examined effects of insulin-signaling in the PiZ mouse model of α1-antitrypsin deficiency (ATD) in which hepatocellular accumulation and proteotoxicity… read more here.
Keywords: piz lirko; mice; insulin signaling; piz ... See more keywords
Diversity and Distribution of Rice Blast (Pyricularia oryzae Cavara) Races in Vietnam.
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DOI: 10.1094/pdis-05-19-1008-re
Abstract: A total of 239 isolates of blast (Pyricularia oryzae Cavara) collected from northern and central Vietnam showed a wide variation in pathogenicity based on the reaction patterns to 25 differential varieties (DVs) harboring 23 resistance… read more here.
Keywords: pik; oryzae cavara; blast pyricularia; piz ... See more keywords
Lunaemycins, New Cyclic Hexapeptide Antibiotics from the Cave Moonmilk-Dweller Streptomyces lunaelactis MM109T
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DOI: 10.3390/ijms24021114
Abstract: Streptomyces lunaelactis strains have been isolated from moonmilk deposits which are calcium carbonate speleothems used for centuries in traditional medicine for their antimicrobial properties. Genome mining revealed that these strains are a remarkable example of… read more here.
Keywords: streptomyces lunaelactis; lunaelactis strains; cyclic hexapeptide; piz ... See more keywords