Differential mechanisms of adenosine‐ and ATPγS‐induced microvascular endothelial barrier strengthening
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DOI: 10.1002/jcp.26419
Abstract: Maintenance of the endothelial cell (EC) barrier is critical to vascular homeostasis and a loss of barrier integrity results in increased vascular permeability. While the mechanisms that govern increased EC permeability have been under intense… read more here.
Keywords: pka activation; barrier; camp; barrier strengthening ... See more keywords
PDE4 and mAKAP&bgr; are nodal organizers of &bgr;2-ARs nuclear PKA signalling in cardiac myocytes
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DOI: 10.1093/cvr/cvy110
Abstract: Aims β1- and β2-adrenergic receptors (β-ARs) produce different acute contractile effects on the heart partly because they impact on different cytosolic pools of cAMP-dependent protein kinase (PKA). They also exert different effects on gene expression… read more here.
Keywords: pka activation; icer; stimulation; pka ... See more keywords