Leptomycin B attenuates neuronal death via PKA- and PP2B-mediated ERK1/2 activation in the rat hippocampus following status epilepticus
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DOI: 10.1016/j.brainres.2017.06.002
Abstract: Leptomycin B (LMB), originally developed as an anti-fungal agent, has potent neuroprotective properties against status epilepticus (SE, a prolonged seizure activity). However, the pharmacological profiles and mechanisms of LMB for neuroprotection remain elusive. In the… read more here.
Keywords: lmb; mediated erk1; neuronal death; pka pp2b ... See more keywords