Curculigoside rescues hippocampal synaptic deficits elicited by PTSD through activating cAMP‐PKA signaling
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7658
Abstract: Chronic traumatic stress results in various psychiatric disorders, especially posttraumatic stress disorder (PTSD). Previous study demonstrated that curculigoside (CUR) a component of Rhizoma Curculiginis prevented fear extinction and stress‐induced depression‐like behaviors. However, its effects on… read more here.
Keywords: pka signaling; signaling pathway; cur; pka ... See more keywords
Mechanism of cAMP-PKA Signaling Pathway Mediated by Shaoyao Gancao Decoction (芍药甘草汤) on Regulation of Aquaporin 5 and Muscarinic Receptor 3 Levels in Sjögren’s Syndrome
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Journal of Integrative Medicine"
DOI: 10.1007/s11655-020-3205-5
Abstract: Objective To investigate the mechanism of cAMP-PKA signaling pathway mediated by Chinese medicine formula Shaoyao Gancao Decoction (芍药甘草汤, SGD) on the regulation of aquaporin 5 (AQP5) and muscarinic receptor 3 (M3R) levels in Sjögren’s syndrome… read more here.
Keywords: medicine; m3r; pka signaling; aqp5 m3r ... See more keywords
Lactobacillus plantarum improves LPS-induced Caco2 cell line intestinal barrier damage via cyclic AMP-PKA signaling
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DOI: 10.1371/journal.pone.0267831
Abstract: Lactobacillus plantarum (LP) has been shown to exhibit protective effects on intestinal barrier function in septic rats, although the regulatory mechanism has not been established. We determined whether LP imparts such protective effects in a… read more here.
Keywords: pka signaling; barrier; lps induced; caco2 ... See more keywords
Dulaglutide impedes depressive-like behavior persuaded by chronic social defeat stress model in male C57BL/6 mice: Implications on GLP-1R and cAMP/PKA signaling pathway in the hippocampus.
Sign Up to like & getrecommendations! Published in 2023 at "Life sciences"
DOI: 10.2139/ssrn.4327439
Abstract: AIM There is a well-founded relation between bullying and depression, which may eventually lead to suicidal behavior. Repurposing of antidiabetic drugs for the treatment of depression started to glow, which open new horizons to introduce… read more here.
Keywords: pka signaling; glp camp; signaling pathway; depression ... See more keywords
Loss of Unconventional Myosin VI Affects cAMP/PKA Signaling in Hindlimb Skeletal Muscle in an Age-Dependent Manner
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.933963
Abstract: Myosin VI (MVI) is a unique unconventional myosin ubiquitously expressed in metazoans. Its diverse cellular functions are mediated by interactions with a number of binding partners present in multi-protein complexes. MVI is proposed to play… read more here.
Keywords: pka signaling; age dependent; muscle; myosin ... See more keywords
FSH/LH-Dependent Upregulation of Ahr in Murine Granulosa Cells Is Controlled by PKA Signaling and Involves Epigenetic Regulation
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20123068
Abstract: The aryl hydrocarbon receptor (Ahr) is a ligand-activated transcription factor primarily known for its toxicological functions. Recent studies have established its importance in many physiological processes including female reproduction, although there is limited data about… read more here.
Keywords: granulosa cells; pka signaling; ahr; upregulation ... See more keywords
Activation of ADRB2/PKA Signaling Pathway Facilitates Lipid Synthesis in Meibocytes, and Beta-Blocker Glaucoma Drug Impedes PKA-Induced Lipid Synthesis by Inhibiting ADRB2
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23169478
Abstract: Meibomian gland dysfunction is one of the main causes of dry eye disease and has limited therapeutic options. In this study, we investigated the biological function of the beta 2-adrenergic receptor (ADRB2)/protein kinase A (PKA)… read more here.
Keywords: lipid synthesis; pka signaling; synthesis; pathway ... See more keywords
cAMP/PKA Signaling Modulates Mitochondrial Supercomplex Organization
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23179655
Abstract: The oxidative phosphorylation (OXPHOS) system couples the transfer of electrons to oxygen with pumping of protons across the inner mitochondrial membrane, ensuring the ATP production. Evidence suggests that respiratory chain complexes may also assemble into… read more here.
Keywords: modulates mitochondrial; pka signaling; production; signaling modulates ... See more keywords