Articles with "pkal inhibitors" as a keyword



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Discovery and development of plasma kallikrein inhibitors for multiple diseases.

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Published in 2020 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2020.112137

Abstract: Plasma kallikrein (PKal) belongs to the family of trypsin-like serine proteases. The expression of PKal is associated with multiple physiological systems or pathways such as coagulation pathway, platelet aggregation process, kallikrein-kinin system, renin-angiotensin system and… read more here.

Keywords: kallikrein; discovery development; pkal inhibitors; plasma kallikrein ... See more keywords