Catestatin in defense of oxidative-stress-induced apoptosis: A novel mechanism by activating the beta2 adrenergic receptor and PKB/Akt pathway in ischemic-reperfused myocardium
Sign Up to like & getrecommendations! Published in 2020 at "Peptides"
DOI: 10.1016/j.peptides.2019.170200
Abstract: Apoptosis induced by oxidative stress is one of the most important cardiomyocytes losses during ischemia-reperfusion (I/R). Catestatin (CST) has been demonstrated to have the anti-oxidative capacity in vitro. We hypothesized that CST intervention could reduce… read more here.
Keywords: reperfused myocardium; apoptosis; cst; pkb akt ... See more keywords
PKB/Akt-dependent regulation of inflammation in cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2017.04.018
Abstract: Chronic inflammation is a major cause of human cancer. Clinical cancer therapies against inflammatory risk factors are strategically determined. To rationally guide a novel drug development, an improved mechanistic understanding on the pathological connection between… read more here.
Keywords: akt dependent; inflammation; dependent regulation; pkb akt ... See more keywords