Inhibitions of PKC and CaMK-II synergistically rescue ischemia-induced astrocytic dysfunction
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DOI: 10.1016/j.neulet.2017.08.017
Abstract: Ischemic neuronal death is presumably caused by glutamate-induced excitotoxicity, in which the increased glutamate release and impaired glutamate reuptake lead to glutamate accumulation. Mechanisms underlying the ischemic deficiency of astrocytic glutamate reuptake remain unclear, which… read more here.
Keywords: glutamate; astrocytic glutamate; ischemia induced; deficiency ... See more keywords