Astragaloside IV inhibits PMA-induced EPCR shedding through MAPKs and PKC pathway
Sign Up to like & getrecommendations! Published in 2017 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2017.1306868
Abstract: Abstract Astragaloside IV (AS-IV), a main active substance isolated from Astragalus membranaceus Bunge, has been shown to have multiple pharmacological effects. Endothelial cell protein C receptor (EPCR) is a marker of inflammation, and is also… read more here.
Keywords: induced epcr; pma induced; pkc pathway; epcr ... See more keywords
D-4F Ameliorates Contrast Media–Induced Oxidative Injuries in Endothelial Cells via the AMPK/PKC Pathway
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.556074
Abstract: Endothelial dysfunction is involved in the pathophysiological processes of contrast media (CM)–induced acute kidney injury (CI-AKI) after vascular angiography or intervention. Previous study found that apolipoprotein A-I (apoA-I) mimetic peptide, D-4F, alleviates endothelial impairments via… read more here.
Keywords: ampk pkc; oxidative injuries; pkc pathway; endothelial cells ... See more keywords