Parathyroid hormone contributes to the down‐regulation of cytochrome P450 3A through the cAMP/PI3K/PKC/PKA/NF‐&kgr;B signaling pathway in secondary hyperparathyroidism
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DOI: 10.1016/j.bcp.2017.08.016
Abstract: ABSTRACT Chronic kidney disease (CKD), which affects, not only renal clearance, but also non‐renal clearance, is accompanied by a decline in renal function. Although it has been suggested that humoral factors, such as uremic toxins… read more here.
Keywords: pth; camp; cyp3a; pkc pka ... See more keywords
Differential Regulation of GPVI-Induced Btk and Syk Activation by PKC, PKA and PP2A in Human Platelets
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DOI: 10.3390/ijms24097776
Abstract: Bruton’s tyrosine kinase (Btk) and spleen tyrosine kinase (Syk) are major signaling proteins in human platelets that are implicated in atherothrombosis and thrombo-inflammation, but the mechanisms controlling their activities are not well understood. Previously, we… read more here.
Keywords: human platelets; pp2a; pkc pka; activation ... See more keywords