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   Articles with "pkc pkc" as a keyword



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PKCγ and PKCε are Differentially Activated and Modulate Neurotoxic Signaling Pathways During Oxygen Glucose Deprivation in Rat Cortical Slices

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recommendations! Published in 2019 at "Neurochemical Research"

DOI: 10.1007/s11064-019-02876-4

Abstract: Cerebral ischemia is known to trigger a series of intracellular events such as changes in metabolism, membrane function and intracellular transduction, which eventually leads to cell death. Many of these processes are mediated by intracellular… read more here.

Keywords: glucose deprivation; cortical slices; oxygen glucose; pkc ... See more keywords
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Differential roles of PKC isoforms (PKCs) in GnRH stimulation of MAPK phosphorylation in gonadotrope derived cells

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recommendations! Published in 2018 at "Molecular and Cellular Endocrinology"

DOI: 10.1016/j.mce.2017.04.004

Abstract: The role of protein kinase C (PKC) isoforms (PKCs) in GnRH-stimulated MAPK [ERK1/2, JNK1/2 and p38) phosphorylation was examined in gonadotrope derived cells. GnRH induced a protracted activation of ERK1/2 and a slower and more… read more here.

Keywords: gonadotrope derived; pkc; derived cells; phosphorylation ... See more keywords
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The roles of PKC-δ and PKC-ε in myocardial ischemia/reperfusion injury.

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recommendations! Published in 2021 at "Pharmacological research"

DOI: 10.1016/j.phrs.2021.105716

Abstract: Ischemia and reperfusion (I/R) cause a reduction in arterial blood supply to tissues, followed by the restoration of perfusion and consequent reoxygenation. The reestablishment of blood flow triggers further damage to ischemic tissue through reactive… read more here.

Keywords: ischemia reperfusion; pkc myocardial; roles pkc; pkc pkc ... See more keywords
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AKF-PD alleviates diabetic nephropathy via blocking the RAGE/AGEs/NOX and PKC/NOX Pathways

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recommendations! Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-36344-w

Abstract: Diabetic nephropathy (DN) is a major complication of diabetes. Currently, drugs are not available to effectively control the disease. Fluorofenidone (AKF-PD) is a recently developed drug; it possesses activities in reducing DN progression in preclinical… read more here.

Keywords: nephropathy via; akf; diabetic nephropathy; akf alleviates ... See more keywords