AB0055 Hydroxychloroquine inhibits soluble cd154 production through ca2+ and pkc signalling pathway
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DOI: 10.1136/annrheumdis-2018-eular.3172
Abstract: Background: Over-expression of membranous CD154 and soluble CD154 (sCD154) in T lymphocytes is important in pathogenesis of autoimmune diseases. PKC pathway induces sCD154 production through promoting shedding of membranous CD154. Objectives: Hydroxychloroquine (HCQ) has been… read more here.
Keywords: production; pkc signalling; cd154; signalling pathway ... See more keywords