Articles with "pkd1 deficient" as a keyword



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Smoking accelerates renal cystic disease and worsens cardiac phenotype in Pkd1-deficient mice

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-93633-7

Abstract: Smoking has been associated with renal disease progression in ADPKD but the underlying deleterious mechanisms and whether it specifically worsens the cardiac phenotype remain unknown. To investigate these matters, Pkd1-deficient cystic mice and noncystic littermates… read more here.

Keywords: cardiac phenotype; worsens cardiac; smoking; pkd1 deficient ... See more keywords