Integrative Approach with Electrophysiological and Theoretical Methods Reveals a New Role of S4 Positively Charged Residues in PKD2L1 Channel Voltage-Sensing
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DOI: 10.1038/s41598-017-10357-3
Abstract: Numerical model-based simulations provide important insights into ion channel gating when experimental limitations exist. Here, a novel strategy combining numerical simulations with patch clamp experiments was used to investigate the net positive charges in the… read more here.
Keywords: voltage; approach electrophysiological; integrative approach; pkd2l1 channel ... See more keywords