Meta-inflammation in monocytes of patients with Acute Coronary Syndrome
Sign Up to like & getrecommendations! Published in 2020 at "European Heart Journal"
DOI: 10.1093/ehjci/ehaa946.1568
Abstract: Several studies suggest that an alteration of monocyte metabolism might be implicated in inflammatory diseases. Enhanced glycolysis might be a hallmark of pro-inflammatory monocyte subsets. Improved glycolysis enables the immune cells to generate sufficient ATP… read more here.
Keywords: pkm; glycolysis; monocytes patients; metabolism ... See more keywords
Impact of hepatitis C treatment status on risk of Parkinson's disease and secondary parkinsonism in the era of direct‐acting antivirals
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Viral Hepatitis"
DOI: 10.1111/jvh.13826
Abstract: Research suggests a possible link between chronic infection with hepatitis C virus (HCV) and the development of Parkinson's Disease (PD) and secondary Parkinsonism (PKM). We investigated the impact of antiviral treatment status (untreated, interferon [IFN]… read more here.
Keywords: risk; hepatitis; treatment status; pkm ... See more keywords
The genetics of PKMζ and memory maintenance
Sign Up to like & getrecommendations! Published in 2017 at "Science Signaling"
DOI: 10.1126/scisignal.aao2327
Abstract: Two atypical PKC isoforms can compensate for each other during short- and long-term memory. Gloss How long-term memories are stored in the brain is a fundamental yet unresolved question in neuroscience. Persistent increases in the… read more here.
Keywords: term memory; pkm; term; long term ... See more keywords
Increased PKMζ activity impedes lateral movement of GluA2-containing AMPA receptors
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Brain"
DOI: 10.1186/s13041-017-0334-7
Abstract: Protein kinase M zeta (PKMζ), a constitutively active, atypical protein kinase C isoform, maintains a high level of expression in the brain after the induction of learning and long-term potentiation (LTP). Further, its overexpression enhances… read more here.
Keywords: glua2 containing; pkm; memory; lateral movement ... See more keywords
Involvement of PKMζ in Stress Response and Depression
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2022.907767
Abstract: The stress system in the brain plays a pivotal role in keeping humans and animals from harmful stimuli. However, excessive stress will cause maladaptive changes to the stress system and lead to depression. Despite the… read more here.
Keywords: stress; stress response; depression; involvement ... See more keywords