The impact of hyperglycaemia on PKM2-mediated NLRP3 inflammasome/stress granule signalling in macrophages and its correlation with plaque vulnerability: an in vivo and in vitro study.
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DOI: 10.1016/j.metabol.2020.154231
Abstract: BACKGROUND The mechanism of pyruvate kinase M2 (PKM2)-mediated inflammatory signalling in macrophages when plaques rupture and the impact of hyperglycaemia on the signalling are unclear. The present study aimed to explore the impact of hyperglycaemia… read more here.
Keywords: nlrp3 inflammasome; hyperglycaemia; stress granule; pkm2 mediated ... See more keywords