PKR activation causes inflammation and MMP-13 secretion in human degenerated articular chondrocytes
Sign Up to like & getrecommendations! Published in 2018 at "Redox Biology"
DOI: 10.1016/j.redox.2017.08.011
Abstract: Osteoarthritis (OA) is a degenerative joint disease affecting a large population of people. Although the elevated expression of PKR (double stranded RNA-dependent protein kinase) and MMP-13 (collagenase-3) have been indicated to play pivotal roles in… read more here.
Keywords: pkr; inflammation mmp; pkr activation;
Activation of PKR by a short-hairpin RNA
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DOI: 10.1038/s41598-024-74477-3
Abstract: Recognition of viral infection often relies on the detection of double-stranded RNA (dsRNA), a process that is conserved in many different organisms. In mammals, proteins such as MDA5, RIG-I, OAS, and PKR detect viral dsRNA,… read more here.
Keywords: pkr activation; activation pkr; pkr; activation ... See more keywords