Evolutionary Dynamics Based on Comparative Genomics of Pathogenic Escherichia coli Lineages Harboring Polyketide Synthase (pks) Island
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DOI: 10.1128/mbio.03634-20
Abstract: Extraintestinal pathologies caused by highly virulent strains of E. coli amount to clinical implications with high morbidity and mortality rates. Pathogenic E. coli strains are evolving with the horizontal acquisition of mobile genetic elements, including… read more here.
Keywords: island; coli; pks positive; clinical implications ... See more keywords
Colibactin: More Than a New Bacterial Toxin
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DOI: 10.3390/toxins10040151
Abstract: Cyclomodulins are bacterial toxins that interfere with the eukaryotic cell cycle. A new cyclomodulin called colibactin, which is synthetized by the pks genomic island, was discovered in 2006. Despite many efforts, colibactin has not yet… read more here.
Keywords: bacterial toxin; pks island; new bacterial; island ... See more keywords