Deletion C-terminal thioesterase abolishes melanin biosynthesis, affects metabolism and reduces the pathogenesis of Fonsecaea monophora
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DOI: 10.1371/journal.pntd.0010485
Abstract: Dematiaceous Fonsecaea monophora is one of the major pathogens of chromoblastomycosis. It has been well established that melanization is catalyzed by the type I polyketide synthase (PKS) in F. monophora. Multidomain protein Type I PKS… read more here.
Keywords: thioesterase; fonsecaea; deletion; fonsecaea monophora ... See more keywords