Articles with "pl1" as a keyword



Structure‐Guided Design and Development of a Phosphinic Lopinavir Analog as a Potent and Selective HIV‐1 Protease Inhibitor

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Published in 2025 at "Journal of Chemistry"

DOI: 10.1155/joch/7113993

Abstract: Human immunodeficiency virus (HIV) remains a significant health issue with no vaccine available. Targeting the HIV‐1 protease (HIV‐1 PR) is essential in treatment, with inhibitors like lopinavir being historically an important component. However, lopinavir alone… read more here.

Keywords: hiv protease; pl1; hiv; lopinavir ... See more keywords