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1
Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1078678
Abstract: Background Melanocortins are peptides endowed with anti-inflammatory and pro-resolving activities. Many of these effects are mediated by the Melanocortin receptor 1 (MC1) as reported in several experimental settings. As such, MC1 can be a viable…
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Keywords:
mc1;
pl8177;
agonist pl8177;
pro resolving ... See more keywords
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2
Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1083333
Abstract: Introduction PL8177 is a potent and selective agonist of the melanocortin 1 receptor (MC1R). PL8177 has shown efficacy in reversing intestinal inflammation in a cannulated rat ulcerative colitis model. To facilitate oral delivery, a novel,…
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Keywords:
pl8177;
formulation;
rats dogs;
melanocortin receptor ... See more keywords