Innate immune TLR7 signaling mediates platelet activation and platelet-leukocyte aggregate formation in murine bacterial sepsis
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DOI: 10.1080/09537104.2022.2107627
Abstract: Abstract Thrombocytopenia is a common complication in sepsis and is associated with higher mortality. Activated platelets express CD62P, which facilitates platelet-leukocyte aggregate (PLA) formation and contributes to thrombocytopenia in sepsis. We have reported that thrombocytopenia… read more here.
Keywords: sepsis; tlr7; platelet activation; pla formation ... See more keywords