Structure of PLA2R reveals presentation of the dominant membranous nephropathy epitope and an immunogenic patch
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DOI: 10.1073/pnas.2202209119
Abstract: Significance • Phospholipase A2 receptor (PLA2R) is the major autoantigen responsible for causing the rare autoimmune kidney disease, membranous nephropathy (MN).• PLA2R autoantibodies primarily bind to a dominant epitope located within a 28-amino acid peptide… read more here.
Keywords: epitope; pla2r; pla2r reveals; structure pla2r ... See more keywords