Inactivating frameshift mutation of putative tumor suppressor genes PLA2R1 and SRPK1 in gastric and colorectal cancers.
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DOI: 10.1016/j.cancergen.2016.11.005
Abstract: To the Editor: Phospholipase A2 receptor 1 (PLA2R1) encodes a transmembrane receptor that plays a role in clearance of phospholipase A2, thereby inhibiting the action of phospholipaseA2 (1). Activation of PLAR1 leads to cellular senescence,… read more here.
Keywords: pla2r1 srpk1; msi; frameshift mutations; cancer ... See more keywords