Clicking into Place: Interfacing Terminal Alkyne Biosynthesis with Polyketide Synthases.
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DOI: 10.1016/j.tibtech.2020.04.001
Abstract: Engineering polyketide biosynthesis to enable the production of diverse chemical structures is a major challenge at present. Utilising an established biosynthetic cassette for terminal alkyne production, Porterfield et al. applied docking domain and site-directed mutagenesis… read more here.
Keywords: clicking place; polyketide; biosynthesis; place interfacing ... See more keywords