[Seeing others is believing-analgesic placebo effects through observational learning?]
Sign Up to like & getrecommendations! Published in 2022 at "Schmerz"
DOI: 10.1007/s00482-022-00646-w
Abstract: BACKGROUND There are many studies on placebo analgesia and its underlying mechanisms that show a significant improvement of care for chronic pain patients. However, observational learning has not been researched to this degree. OBJECTIVES The goal… read more here.
Keywords: placebo effects; observational learning; placebo; placebo analgesia ... See more keywords
Cutoff criteria for the placebo response: a cluster and machine learning analysis of placebo analgesia
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DOI: 10.1038/s41598-021-98874-0
Abstract: Computations of placebo effects are essential in randomized controlled trials (RCTs) for separating the specific effects of treatments from unspecific effects associated with the therapeutic intervention. Thus, the identification of placebo responders is important for… read more here.
Keywords: machine learning; analysis; placebo analgesia; placebo ... See more keywords
Placebo Analgesia as Nocebo Reduction
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DOI: 10.1080/21507740.2018.1499682
Abstract: In the target article “Telling the Truth About Pain: Informed Consent and the Role of Expectation in Pain Intensity,” evidence of pain as “a psychological phenomenon causally related to physical or biological changes” supports the… read more here.
Keywords: placebo; use placebo; placebo analgesia; expectation ... See more keywords
The effect of the model's social status on placebo analgesia induced by social observational learning.
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DOI: 10.1093/pm/pnab299
Abstract: BACKGROUND Placebo analgesia can be induced by social observational learning. The aim of this study was to determine whether this effect can be influenced by the social status of a model. METHODS Healthy volunteers were… read more here.
Keywords: status; analgesia induced; placebo analgesia; model ... See more keywords
Escalating morphine dosage fails to elicit conditioned analgesia in a preclinical chronic neuropathic pain model
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DOI: 10.1097/fbp.0000000000000642
Abstract: Many people with chronic pain escalate their opioid dosage to counteract tolerance effects. A treatment regimen consisting of placebos admixed with opioids has been suggested as a possible therapeutic option that could reduce the harm… read more here.
Keywords: escalating morphine; pain; placebo analgesia; conditioning ... See more keywords
Open-label nondeceptive placebo analgesia is blocked by the opioid antagonist naloxone.
Sign Up to like & getrecommendations! Published in 2022 at "Pain"
DOI: 10.1097/j.pain.0000000000002791
Abstract: ABSTRACT Open-label placebos, or placebos without deception, have been found to induce analgesia, a challenging concept that need to be investigated in detail. In particular, what we need to know is the mechanism through which… read more here.
Keywords: placebo analgesia; open label; naloxone; placebo ... See more keywords
Savor the flavor: A randomized double‐blind study assessing taste‐enhanced placebo analgesia in healthy volunteers
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DOI: 10.1111/cts.13397
Abstract: Placebo effects substantially contribute to analgesic treatment outcomes and might be leveraged to enhance gold‐standard treatments. The taste of oral medications has been proposed to boost placebo effects. Here, we aimed at estimating how far… read more here.
Keywords: taste; randomized double; placebo; double blind ... See more keywords
Are Individual Learning Experiences More Important Than Heritable Tendencies? A Pilot Twin Study on Placebo Analgesia
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DOI: 10.3389/fpsyt.2019.00679
Abstract: Objective: Predicting who will be a placebo responder is a prerequisite to maximize placebo effects in pain treatment and to minimize them in clinical trials. First evidence exists that genetics could affect placebo effects. However,… read more here.
Keywords: placebo; placebo analgesia; individual learning; twin study ... See more keywords