Placebo Control and Blinding in Randomized Trials of Procedural Interventions: A Systematic Review and Meta-Regression.
Sign Up to like & getrecommendations! Published in 2024 at "JAMA surgery"
DOI: 10.1001/jamasurg.2024.0718
Abstract: Importance Unlike medications, procedural interventions are rarely trialed against placebo prior to becoming accepted in clinical practice. When placebo-controlled trials are eventually conducted, procedural interventions may be less effective than previously believed. Objective To investigate… read more here.
Keywords: end; end points; procedural interventions; placebo ... See more keywords
Intestinal mucosal bacterial diversity of antibiotic-associated diarrhea (AAD) mice treated with Debaryomyces hansenii and Qiweibaizhu powder
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DOI: 10.1007/s13205-020-02383-2
Abstract: The aim was to investigate the combined effect of Debaryomyces hansenii and Qiweibaizhu powder (QWBZP) on the bacterial diversity of the intestinal mucosa of antibiotic-associated diarrhea (AAD) mice, for the potential treatment of diarrhea, especially… read more here.
Keywords: treatment; intestinal mucosal; group; placebo control ... See more keywords
Problems of scientific methodology related to placebo control in Qigong studies: A systematic review.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of bodywork and movement therapies"
DOI: 10.1016/j.jbmt.2020.06.035
Abstract: INTRODUCTION Qigong is widespread in the West and used for preventive care, stress-induced conditions, emotional and vegetative symptoms like migraine and hypertension, as well as for better coordination in the elderly and quality of life… read more here.
Keywords: placebo; methodology; systematic review; placebo control ... See more keywords
Masking Influences: A Systematic Review of Placebo Control and Masking in Psychedelic Studies.
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DOI: 10.1080/02791072.2024.2424272
Abstract: Psychedelic-assisted therapy is becoming increasingly acknowledged as an effective therapeutic intervention for various psychiatric illnesses. However, the evaluation of masking success is rarely reported in trials. The objective of the present systematic review was to… read more here.
Keywords: systematic review; masking influences; control masking; placebo ... See more keywords
Advice to the FDA to Improve Its Proposed Guidelines to Rationalize Clinical Trials by Restricting Placebo Control, Preventing Low-Powered Studies, and Disallowing Studies Where Bioavailability Is Not Proven
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DOI: 10.3390/ph17111424
Abstract: Randomized controlled trials (RCTs) are the gold standard for testing the safety and efficacy of new drugs and biologicals. The US Food and Drug Administration (FDA) has proactively improved the trial designs to make them… read more here.
Keywords: advice fda; clinical trials; placebo; placebo control ... See more keywords