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Published in 2023 at "Clinical and Translational Allergy"
DOI: 10.1002/clt2.12226
Abstract: Abstract Background Cold urticaria (ColdU) is characterized by pruritic wheals following exposure of the skin to cold. Many patients show insufficient response to antihistamines, the first line treatment. Based on the high efficacy of interleukin‐1(IL‐1)‐inhibition…
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Keywords:
inhibition;
placebo;
rilonacept;
cold urticaria ... See more keywords
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Published in 2019 at "Cancer"
DOI: 10.1002/cncr.32340
Abstract: Src signaling is markedly upregulated in patients with invasive glioblastoma (GBM) after the administration of bevacizumab. The Src family kinase inhibitor dasatinib has been found to effectively block bevacizumab‐induced glioma invasion in preclinical models, which…
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Keywords:
bevacizumab;
placebo controlled;
randomized placebo;
phase randomized ... See more keywords
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Published in 2018 at "Depression and Anxiety"
DOI: 10.1002/da.22728
Abstract: The purpose of this study was to examine the efficacy of cognitive behavioral therapy (CBT) for anxiety‐related disorders based on randomized placebo‐controlled trials. We included 41 studies that randomly assigned patients (N = 2,843) with…
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Keywords:
cognitive behavioral;
anxiety;
placebo controlled;
disorder ... See more keywords
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Published in 2022 at "Drug testing and analysis"
DOI: 10.1002/dta.3370
Abstract: Hematological results in the context of the Athlete Biological Passport (ABP) from a placebo-controlled EPO administration study are provided here. Twelve participants administered eight subcutaneous boosting doses of epoetin alfa (at 40 IU/kg) over the…
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Keywords:
athlete biological;
placebo;
passport;
placebo controlled ... See more keywords
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Published in 2022 at "Epilepsia Open"
DOI: 10.1002/epi4.12656
Abstract: To characterize efficacy, safety/tolerability, and pharmacokinetics of padsevonil (PSL) administered concomitantly with ≤3 antiseizure medications (ASMs) for observable focal seizures in adults with drug‐resistant epilepsy in two multicenter, randomized, double‐blind, placebo‐controlled, parallel‐group trials.
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Keywords:
double blind;
adults drug;
placebo controlled;
drug resistant ... See more keywords
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Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26410
Abstract: This network meta‐analysis was conducted to compare effects of different placebo‐controlled insulin‐sensitizing drugs, including metformin, pioglitazone, rosiglitazone, and troglitazone on hormonal parameters in polycystic ovary syndrome (PCOS) patients. We searched PubMed, EMBASE, and Cochrane Library…
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Keywords:
placebo controlled;
analysis;
insulin sensitizing;
controlled insulin ... See more keywords
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Published in 2022 at "Journal of clinical pharmacology"
DOI: 10.1002/jcph.2035
Abstract: The use of placebo concurrent control (placebo-controlled) is the most rigorous method of evaluating the safety and efficacy of investigational treatments. However, the use of a placebo group in pediatric product development can be challenging…
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Keywords:
placebo response;
response;
placebo controlled;
adult ... See more keywords
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Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7375
Abstract: The present study conducted a placebo‐controlled clinical trial to evaluate the impact of nano‐curcumin on the inflammatory cytokines in mild‐to‐moderate hospitalized COVID‐19 patients. A total of 60 COVID‐19 patients were randomly divided into nano‐curcumin and…
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Keywords:
covid patients;
curcumin;
placebo controlled;
clinical trial ... See more keywords
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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7498-6_28
Abstract: This chapter describes the methodologies which may be used in the development of a randomized controlled trial investigating a therapy of choice in preventing preeclampsia.
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Keywords:
double blinded;
trial;
randomized double;
placebo controlled ... See more keywords
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Published in 2021 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-021-03074-4
Abstract: Complete remission (CR) of acute myeloid leukemia (AML) in elderly patients has a short duration, and there is no suitable post-remission therapy. We explored the role of the Wilms’ tumor 1 helper peptide OCV-501 to…
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Keywords:
peptide;
placebo controlled;
myeloid leukemia;
acute myeloid ... See more keywords
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Published in 2019 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-019-03880-9
Abstract: PurposeTo evaluate the effect of lapatinib on the QTc interval and ECG parameters in patients with advanced solid tumors.MethodsThis was a multicenter, placebo-controlled study in subjects with advanced solid tumors. Subjects were administered two doses…
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Keywords:
advanced solid;
solid tumors;
placebo controlled;
study ... See more keywords