Raising Placebo Efficacy in Antidepressant Trials Across Decades Explained by Small-Study Effects: A Meta-Reanalysis
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DOI: 10.3389/fpsyt.2020.00633
Abstract: Background Recent meta-analyses reported placebo response rate in antidepressant trials to be stable since the 1970s. These meta-analyses however were limited in considering only linear time trends, assessed trial-level covariates based on single-model hypothesis testing… read more here.
Keywords: placebo efficacy; small study; time trends; study effects ... See more keywords