Human placenta‐derived mesenchymal stem cells induce trophoblast invasion via dynamic effects on mitochondrial function
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30330
Abstract: The trophoblast is a critical cell for placental development and embryo implantation in the placenta. We previously reported that placenta‐derived mesenchymal stem cells (PD‐MSCs) increase trophoblast invasion through several signaling pathways. However, the paracrine effects… read more here.
Keywords: derived mesenchymal; trophoblast invasion; invasion; mitochondrial function ... See more keywords
Alteration of Placental Deiodinase 3 Expression by BDE 209 and Possible Protection by Taurine in Human Placenta-Derived JEG Cells Under Hypoxia.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-8023-5_67
Abstract: Thyroid hormones are key hormones involved in growth and development. Changes in their levels can cause embryonic brain developmental damage in the first trimester. Studies have shown that polybrominated diphenyl ethers (PBDEs) have developmental neurotoxicity… read more here.
Keywords: derived jeg; human placenta; jeg cells; placenta derived ... See more keywords
A genetic variant in the placenta-derived MHC class I chain-related gene A increases the risk of preterm birth in a Chinese population
Sign Up to like & getrecommendations! Published in 2017 at "Human Genetics"
DOI: 10.1007/s00439-017-1834-3
Abstract: Preterm birth (PTB) is a predominant contributor to neonatal mortality and morbidity worldwide. However, the pathophysiology of PTB is not well-understood. We tested the hypothesis that single-nucleotide polymorphisms (SNPs) in the placenta-derived MHC class I… read more here.
Keywords: ptb; class chain; preterm birth; derived mhc ... See more keywords
Cartilage repair by various concentrations of placenta-derived mesenchymal stem cells and hyaluronic acid hydrogels in a rabbit model
Sign Up to like & getrecommendations! Published in 2017 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2020.03.375
Abstract: Background & Aim The placenta-derived mesenchymal stem cells have great interest as a promising cell source for regenerative medicine due to non-invasive collection, readily availability, high expansion capacity, and low immunogenicity. We investigated the feasibility… read more here.
Keywords: cartilage repair; 107 cells; hyaluronic acid; placenta derived ... See more keywords
3D-cultured human placenta-derived mesenchymal stem cell spheroids enhance ovary function by inducing folliculogenesis
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-33575-9
Abstract: Placenta-derived mesenchymal stem cells (PD-MSCs) have numerous advantages over other adult MSCs that make them an attractive cell source for regenerative medicine. Here, we demonstrate the therapeutic effect of PD-MSCs in ovariectomized (Ovx) rats and… read more here.
Keywords: derived mesenchymal; placenta derived; group; stem ... See more keywords
Small RNA sequencing reveals placenta-derived exosomal microRNAs associated with preeclampsia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Hypertension"
DOI: 10.1097/hjh.0000000000003112
Abstract: Objective: Preeclampsia is one of the most important complications during pregnancy and the leading cause of maternal morbidity and mortality; however, the pathogenesis of preeclampsia remains partially misunderstood. The aim of this study was to… read more here.
Keywords: derived exosomal; rna sequencing; differentially expressed; preeclampsia ... See more keywords
Conquering the cytokine storm in COVID-19-induced ARDS using placenta-derived decidua stromal cells.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cellular and molecular medicine"
DOI: 10.1111/jcmm.16986
Abstract: Acute respiratory distress syndrome (ARDS) is the most common cause of death in COVID-19 patients. The cytokine storm is the main driver of the severity and magnitude of ARDS. Placenta-derived decidua stromal cells (DSCs) have… read more here.
Keywords: range; stromal cells; derived decidua; cytokine storm ... See more keywords
High Proliferative Placenta-Derived Multipotent Cells Express Cytokeratin 7 at Low Level
Sign Up to like & getrecommendations! Published in 2019 at "BioMed Research International"
DOI: 10.1155/2019/2098749
Abstract: The purpose of this study was to investigate the immunophenotypes and gene expression profile of high proliferative placenta-derived multipotent cells (PDMCs) population at different stages of culture. We demonstrated that the colonies resulting from single… read more here.
Keywords: ck7low clones; placenta derived; high proliferative; ck7 ... See more keywords
Placental Stem Cells from Domestic Animals
Sign Up to like & getrecommendations! Published in 2018 at "Cell Transplantation"
DOI: 10.1177/0963689717724797
Abstract: The field of regenerative medicine is moving toward clinical practice in veterinary science. In this context, placenta-derived stem cells isolated from domestic animals have covered a dual role, acting both as therapies for patients and… read more here.
Keywords: medicine; cell; domestic animals; placenta derived ... See more keywords
Placenta-Derived Exosomes as a Modulator in Maternal Immune Tolerance During Pregnancy
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.671093
Abstract: Exosomes are a subset of extracellular vesicles with an average diameter of ~100nm. Exosomes are released by all cells through an endosome-dependent pathway and carry nucleic acids, proteins, lipids, cytokines and metabolites, mirroring the state… read more here.
Keywords: maternal immune; pregnancy; immune tolerance; placenta derived ... See more keywords
Effect of Placenta-Derived Mesenchymal Stromal Cells Conditioned Media on an LPS-Induced Mouse Model of Preeclampsia
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031674
Abstract: We tested the pro-angiogenic and anti-inflammatory effects of human placenta-derived mesenchymal stromal cells (hPDMSCs)-derived conditioned media (CM) on a mouse model of preeclampsia (PE), a severe human pregnancy-related syndrome characterized by maternal hypertension, proteinuria, endothelial… read more here.
Keywords: conditioned media; mesenchymal stromal; derived mesenchymal; placenta derived ... See more keywords