Pericytes in the Placenta: Role in Placental Development and Homeostasis.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-11093-2_8
Abstract: The placenta is the most variable organ, in terms of structure, among the species. Besides it, all placental types have the same function: production of viable offspring, independent of pregnancy length, litter number, or invasion… read more here.
Keywords: placental development; role placental; development homeostasis; development ... See more keywords
Gestational exposure to acrylamide inhibits mouse placental development in vivo.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2018.12.061
Abstract: Acrylamide, a carcinogen and neurotoxic substance, recently has been discovered in various heat-treated carbohydrate-rich foods. The aim of this study was to investigate the effects of acrylamide exposure on placental development. Pregnant mice received acrylamide… read more here.
Keywords: placental development; exposure acrylamide; gestational exposure; exposure ... See more keywords
Notch signalling in placental development and gestational diseases.
Sign Up to like & getrecommendations! Published in 2017 at "Placenta"
DOI: 10.1016/j.placenta.2017.01.117
Abstract: Activation of Notch signalling upon cell-cell contact of neighbouring cells controls a plethora of cellular processes such as stem cell maintenance, cell lineage determination, cell proliferation, and survival. Accumulating evidence suggests that the pathway also… read more here.
Keywords: notch signalling; placental development; gestational diseases; notch ... See more keywords
Paternal low protein diet and the supplementation of methyl-donors impact fetal growth and placental development in mice.
Sign Up to like & getrecommendations! Published in 2020 at "Placenta"
DOI: 10.1016/j.placenta.2020.10.020
Abstract: INTRODUCTION Paternal low-protein diet can alter sperm methylation status, fetal growth and program offspring ill-health, however its impact on the placenta remains poorly defined. Here we examine the influence paternal low-protein diet has on fetal… read more here.
Keywords: protein; low protein; protein diet; placental development ... See more keywords
Placental structural abnormalities in gestational diabetes and when they develop: A scoping review.
Sign Up to like & getrecommendations! Published in 2021 at "Placenta"
DOI: 10.1016/j.placenta.2021.04.005
Abstract: Gestational diabetes mellitus (GDM) is defined as diabetes with onset or first recognition during gestation. It is a common complication of pregnancy that has become more prevalent over the past few decades. Abnormalities in fetal… read more here.
Keywords: gestational diabetes; scoping review; gdm pregnancies; placental development ... See more keywords
Liquid crystal monomers induce placental development and progesterone release dysregulation through transplacental transportation
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-56552-z
Abstract: Embryonic and fetal development can be affected during gestation by exposure to xenobiotics that cross the placenta. Liquid crystal monomers (LCMs) are emerging contaminants commonly found in indoor environments; however, whether they can cross the… read more here.
Keywords: placental development; development; transplacental transportation; progesterone release ... See more keywords
PIEZO1 drives trophoblast fusion and placental development
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-62254-3
Abstract: PIEZO1, a mechanosensor in endothelial cells, plays a critical role in fetal vascular development during embryogenesis. However, its expression and function in placental trophoblasts remain unexplored. Here, we demonstrate that PIEZO1 is expressed in placental… read more here.
Keywords: placental development; development; fusion placental; trophoblast fusion ... See more keywords
Advanced magnetic resonance imaging detects altered placental development in pregnancies affected by congenital heart disease
Sign Up to like & getrecommendations! Published in 2024 at "Scientific Reports"
DOI: 10.1038/s41598-024-63087-8
Abstract: Congenital heart disease (CHD) is the most common congenital malformation and is associated with adverse neurodevelopmental outcomes. The placenta is crucial for healthy fetal development and placental development is altered in pregnancy when the fetus… read more here.
Keywords: placental development; development; congenital heart; heart disease ... See more keywords
Sexual dimorphism in placental development and its contribution to health and diseases.
Sign Up to like & getrecommendations! Published in 2021 at "Critical reviews in toxicology"
DOI: 10.1080/10408444.2021.1977237
Abstract: According to the Developmental Origin of Health and Disease (DOHaD), intrauterine exposure to adverse environments can affect fetus and birth outcomes and lead to long-term disease susceptibility. Evidence has shown that neonatal outcomes and the… read more here.
Keywords: placental development; sexual dimorphism; health; development ... See more keywords
Effects of L-carnitine on reproductive performance, milk composition, placental development and IGF concentrations in blood plasma and placental chorions in sows
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Animal Nutrition"
DOI: 10.1080/1745039x.2018.1471185
Abstract: ABSTRACT Recent studies have shown that L-carnitine supplementation of sows during pregnancy and lactation enhances their reproductive performance, but the underlying mechanisms are still needed to be further confirmed. This study was conducted to investigate… read more here.
Keywords: placental development; reproductive performance; placental chorions; carnitine treated ... See more keywords
213 Comparative single-cell transcriptomics uncovers key regulatory mechanisms in bovine placental development.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Animal Science"
DOI: 10.1093/jas/skaf300.104
Abstract: Pregnancy loss in cattle imposes a significant financial burden on producers. Successful pregnancy relies on a complex interplay of biological processes, including the development and maintenance of the placenta. The placenta facilitates nutrient transport, gas… read more here.
Keywords: placental development; pregnancy loss; single cell; cell ... See more keywords