Human placental gene sets improve analysis of placental pathologies and link trophoblast and cancer invasion genes.
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DOI: 10.1016/j.placenta.2021.06.011
Abstract: INTRODUCTION Interpretation of gene expression uses set enrichment or overrepresentation methods that depend on sets of annotated genes, such as the popular Gene Ontology. The placenta is understudied relative to other major organs creating a… read more here.
Keywords: ontology; placental pathologies; human placental; placental gene ... See more keywords
Placental gene expression and antibody levels of mother-neonate pairs reveal an enhanced risk for inflammation in a helminth endemic country
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DOI: 10.1038/s41598-019-52074-z
Abstract: In utero exposure to environmental factors can modify the development of allergies later in life whereby the mechanisms of the feto-maternal crosstalk still remain largely unknown. Murine studies revealed that inflammatory maternal signals elicited by… read more here.
Keywords: helminth endemic; inflammation; gene expression; placental gene ... See more keywords
Placental Gene Co-expression Network for Maternal Plasma Lipids Revealed Enrichment of Inflammatory Response Pathways
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DOI: 10.3389/fgene.2021.681095
Abstract: Maternal dyslipidemia during pregnancy has been associated with suboptimal fetal growth and increased cardiometabolic diseasse risk in offspring. Altered placental function driven by placental gene expression is a hypothesized mechanism underlying these associations. We tested… read more here.
Keywords: network; analysis; gene expression; placental gene ... See more keywords