340. Quercetin protects against the vascular contractile effect of placental secreted messengers released under placental hypoxia
Sign Up to like & getrecommendations! Published in 2018 at "Pregnancy Hypertension"
DOI: 10.1016/j.preghy.2018.08.385
Abstract: Introduction Hypoxia is a crucial factor in the pathogenesis of preeclampsia resulting in hypoxic stress in the placenta. Upon this stress the placenta will release placenta secreted messengers (PSMs) which will cause maternal endothelial dysfunction.… read more here.
Keywords: secreted messengers; effect; placental hypoxia; psms released ... See more keywords
Obesity during pregnancy results in maternal intestinal inflammation, placental hypoxia, and alters fetal glucose metabolism at mid-gestation
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-54098-x
Abstract: We investigated whether diet-induced changes in the maternal intestinal microbiota were associated with changes in bacterial metabolites and their receptors, intestinal inflammation, and placental inflammation at mid-gestation (E14.5) in female mice fed a control (17%… read more here.
Keywords: maternal intestinal; inflammation; mid gestation; placental hypoxia ... See more keywords
Paternal obesity induces placental hypoxia and sex-specific impairments in placental vascularization and offspring metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioac066
Abstract: Abstract Paternal obesity predisposes offspring to metabolic dysfunction, but the underlying mechanisms remain unclear. We investigated whether this metabolic dysfunction is associated with changes in placental vascular development and is fueled by endoplasmic reticulum (ER)… read more here.
Keywords: obesity induces; placental hypoxia; paternal obesity; sex specific ... See more keywords