Mitochondrial DNA content and methylation in fetal cord blood of pregnancies with placental insufficiency.
Sign Up to like & getrecommendations! Published in 2017 at "Placenta"
DOI: 10.1016/j.placenta.2017.05.008
Abstract: INTRODUCTION Intrauterine growth restriction (IUGR) and preeclampsia (PE) are pregnancy disorders characterized by placental insufficiency with oxygen/nutrient restriction and oxidative stress, all influencing mitochondria functionality and number. Moreover, IUGR and PE fetuses are predisposed to… read more here.
Keywords: methylation; placental insufficiency; cord blood; dna ... See more keywords
Diagnosis of placental insufficiency independently of clinical presentations using sFlt-1/PLGF ratio, including SGA patients.
Sign Up to like & getrecommendations! Published in 2021 at "Pregnancy hypertension"
DOI: 10.1016/j.preghy.2021.07.245
Abstract: INTRODUCTION Angiogenic markers (sFLt1 and PlGF) are altered in preeclampsia and related placental insufficiency syndromes. The utility of these markers in various types of placental insufficiency is still not well known. AIMS We analyzed blood… read more here.
Keywords: sflt1 plgf; sflt plgf; sga; plgf ratio ... See more keywords
Exposure to placental insufficiency alters postnatal growth trajectory in extremely low birth weight infants
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Developmental Origins of Health and Disease"
DOI: 10.1017/s2040174419000564
Abstract: Abstract Growth in the immediate postnatal period for extremely low birth weight (ELBW, birth weight < 1000 g) infants is an important topic in neonatal medicine. The goal is to ensure adequate postnatal growth and… read more here.
Keywords: birth weight; growth; placental insufficiency;
Results of full postmortem examination in a cohort of clinically unexplained stillbirths: undetected fetal growth restriction and placental insufficiency are prevalent findings
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Perinatology"
DOI: 10.1038/s41372-019-0412-z
Abstract: To analyze a cohort of clinically unexplained stillbirths (CUS) referred for postmortem. In total, 258 CUS were referred for full postmortem between 2009 and 2015. Relevant Condition at Death (ReCoDe) classification was applied. Statistical analysis… read more here.
Keywords: fetal growth; growth; growth restriction; placental insufficiency ... See more keywords
Potentially Preventable Stillbirth in a Diverse U.S. Cohort.
Sign Up to like & getrecommendations! Published in 2018 at "Obstetrics and gynecology"
DOI: 10.1097/aog.0000000000002421
Abstract: OBJECTIVE To estimate the proportion of potentially preventable stillbirths in the United States. METHODS We conducted a secondary analysis of 512 stillbirths with complete evaluation enrolled in the Stillbirth Collaborative Research Network from 2006 to… read more here.
Keywords: potentially preventable; preventable stillbirth; placental insufficiency; cohort ... See more keywords
Mechanisms of Fetal Adaptation to Chronic Hypoxia following Placental Insufficiency: A Review
Sign Up to like & getrecommendations! Published in 2022 at "Fetal Diagnosis and Therapy"
DOI: 10.1159/000525717
Abstract: Placental insufficiency is associated with reduced oxygen and nutrient supply to the fetus, which may result in fetal growth restriction (FGR). In an attempt to cope with the hostile intrauterine environment, FGR fetuses respond through… read more here.
Keywords: placental insufficiency; mechanisms fetal; fetal adaptation; adaptation chronic ... See more keywords
Antiphospholipid antibodies in women with severe preeclampsia and placental insufficiency: a case-control study
Sign Up to like & getrecommendations! Published in 2018 at "Lupus"
DOI: 10.1177/0961203318787035
Abstract: Objective Preterm delivery for preeclampsia or placental insufficiency (PREPI) is a clinical criterion for antiphospholipid syndrome (APS), but no prior prospective studies have used the international classification criteria for APS. Our objective is to determine… read more here.
Keywords: control study; study; apl; case control ... See more keywords
Identification of key genes in pathogenesis of placental insufficiency intrauterine growth restriction
Sign Up to like & getrecommendations! Published in 2022 at "BMC Pregnancy and Childbirth"
DOI: 10.1186/s12884-022-04399-3
Abstract: Background Intrauterine growth restriction (IUGR) is defined as a fetus that fails to achieve its genetically determined growth potential. The exact molecular mechanisms of placental insufficiency IUGR pathogenesis are a little known. Our goal was… read more here.
Keywords: insufficiency iugr; placental insufficiency; network; insufficiency ... See more keywords
Reduced growth velocity across the third trimester is associated with placental insufficiency in fetuses born at a normal birthweight: a prospective cohort study
Sign Up to like & getrecommendations! Published in 2017 at "BMC Medicine"
DOI: 10.1186/s12916-017-0928-z
Abstract: BackgroundWhile being small-for-gestational-age due to placental insufficiency is a major risk factor for stillbirth, 50% of stillbirths occur in appropriate-for-gestational-age (AGA, > 10th centile) fetuses. AGA fetuses are plausibly also at risk of stillbirth if placental… read more here.
Keywords: growth velocity; growth; placental insufficiency; centile ... See more keywords
Circulating mRNAs are differentially expressed in pregnancies with severe placental insufficiency and at high risk of stillbirth
Sign Up to like & getrecommendations! Published in 2020 at "BMC Medicine"
DOI: 10.1186/s12916-020-01605-x
Abstract: Background Fetuses affected by placental insufficiency do not receive adequate nutrients and oxygenation, become growth restricted and acidemic, and can demise. Preterm fetal growth restriction is a severe form of placental insufficiency with a high… read more here.
Keywords: insufficiency; fetal growth; growth restriction; placental insufficiency ... See more keywords
Stillbirths preceded by reduced fetal movements are more frequently associated with placental insufficiency: a retrospective cohort study
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Perinatal Medicine"
DOI: 10.1515/jpm-2021-0103
Abstract: Abstract Objectives Maternal report of reduced fetal movements (RFM) is a means of identifying fetal compromise in pregnancy. In live births RFM is associated with altered placental structure and function. Here, we explored associations between… read more here.
Keywords: reduced fetal; fetal movements; insufficiency; stillbirth ... See more keywords