Disrupted placental serotonin synthetic pathway and increased placental serotonin: Potential implications in the pathogenesis of human fetal growth restriction.
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DOI: 10.1016/j.placenta.2019.05.012
Abstract: OBJECTIVES Placental insufficiency contributes to altered maternal-fetal amino acid transfer, and thereby to poor fetal growth. An important placental function is the uptake of tryptophan and its metabolism to serotonin (5-HT) and kynurenine metabolites, which… read more here.
Keywords: control; fetal growth; growth restriction; placental serotonin ... See more keywords