Placental disposition of the immunosuppressive drug tacrolimus in renal transplant recipients and in ex vivo perfused placental tissue
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.04.017
Abstract: ABSTRACT Currently, tacrolimus is the most potent immunosuppressive agent for renal transplant recipients and is commonly prescribed during pregnancy. As data on placental exposure and transfer are limited, we studied tacrolimus placental handling in samples… read more here.
Keywords: transplant recipients; renal transplant; placental disposition; placental tissue ... See more keywords
Epigenetic changes occur in placentas of spontaneous and recurrent miscarriages.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of reproductive immunology"
DOI: 10.1016/j.jri.2021.103466
Abstract: BACKGROUND In contrast to genetic abnormalities which are well known to be responsible for around 50 % of human miscarriages, there is very few data about epigenetic alterations in spontaneous and recurrent miscarriages (SM, RM).… read more here.
Keywords: h3k4me3 h3k9ac; recurrent miscarriages; h3k4me3; placental tissue ... See more keywords
Expression of HLA-E molecules in the placental tissue of women infected with HIV-1 and uninfected women.
Sign Up to like & getrecommendations! Published in 2017 at "Placenta"
DOI: 10.1016/j.placenta.2016.08.082
Abstract: INTRODUCTION Expression of HLA-E molecule in the placental extravillous trophoblast is associated with immune system cell inhibition, resulting in immune tolerance to fetus during pregnancy. HIV-1 can infect trophoblast cells and modify the expression of… read more here.
Keywords: expression hla; hiv; placental tissue; hla ... See more keywords
Histopathologic Changes in Placental Tissue Associated With Vertical Transmission of Zika Virus
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DOI: 10.1097/pgp.0000000000000586
Abstract: Zika virus (ZIKV) is highly neurotropic after crossing the placenta, inducing teratogenic effects that result in delayed development and microcephaly in infants. The available evidence for vertical transmission of this infection is based on placental… read more here.
Keywords: transmission; zika virus; vertical transmission; tissue ... See more keywords
Human Placental Tissue Contains A Placental Lactogen–Derived Vasoinhibin
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvac029
Abstract: Abstract Hormonal factors affecting the vascular adaptions of the uteroplacental unit in noncomplicated and complicated pregnancies are of interest. Here, 4 human placentas from women with and without preeclampsia (PE) were investigated for the presence… read more here.
Keywords: placental lactogen; derived vasoinhibin; lactogen derived; placental tissue ... See more keywords
Increase in short telomeres during the third trimester in human placenta
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DOI: 10.1371/journal.pone.0271415
Abstract: An increase in telomere shortening in gestational tissues has been proposed as a mechanism involved in the timing for the initiation of parturition. An increase in very short telomeres with increasing gestational age has been… read more here.
Keywords: increase short; increase; short telomeres; term ... See more keywords
Expression pattern and clinical significance of microRNA-let-7a and IFN-gamma in placental tissue of patients with preeclampsia with severe features
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Perinatal Medicine"
DOI: 10.1515/jpm-2021-0133
Abstract: Abstract Objectives Preeclampsia with severe features (PECsf) is a common disease in pregnant women. let-7a and IFN-gamma (interferon-gamma) are involved in diagnosis and prognosis of preeclampsia. This study explored effects of let-7a and IFN-gamma on… read more here.
Keywords: let ifn; group; ifn gamma; placental tissue ... See more keywords
Alterations in Antioxidant Micronutrient Concentrations in Placental Tissue, Maternal Blood and Urine and the Fetal Circulation in Pre-eclampsia
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DOI: 10.3390/ijms24043579
Abstract: Trace elements such as selenium and zinc are vital components of many enzymes, including endogenous antioxidants, and can interact with each other. Women with pre-eclampsia, the hypertensive disease of pregnancy, have been reported as having… read more here.
Keywords: women pre; plasma; pre eclampsia; selenium zinc ... See more keywords
Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) including Variant Analysis by Mass Spectrometry in Placental Tissue
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DOI: 10.3390/v14030604
Abstract: Among neonates, tested positive for SARS-CoV-2, the majority of infections occur through postpartum transmission. Only few reports describe intrauterine or intrapartum SARS-CoV-2 infections in newborns. To understand the route of transmission, detection of the virus… read more here.
Keywords: mass spectrometry; detection; placental tissue; sars cov ... See more keywords
Effects of vitrification on the imprinted gene Snrpn in neonatal placental tissue
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DOI: 10.4103/2096-2924.281851
Abstract: Objective: To investigate the effects of vitrification on the expression of the imprinted gene Snrpn in neonatal placental tissue.Methods: Neonatal placental tissue was collected from women with natural pregnancy (control group) and from women in… read more here.
Keywords: gene snrpn; snrpn; imprinted gene; placental tissue ... See more keywords
Overexpression of glycolysis markers in placental tissue of pregnant women with chronic venous disease: a histological study
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Medical Sciences"
DOI: 10.7150/ijms.65419
Abstract: Chronic Venous Disease (CVD) refers to a wide variety of venous disorders being the varicose veins its most common manifestation. It is well-established the link between pregnancy and the risk of suffering CVD, due to… read more here.
Keywords: tissue pregnant; venous disease; pregnant women; chronic venous ... See more keywords