Pediatric lipoblastoma with a novel EEF1A1‐PLAG1 fusion
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DOI: 10.1002/gcc.22945
Abstract: To the Editor: We read with interest the recent study by Chung et al reporting three distinctive myxoid-fibroblastic soft tissue tumors in children characterized by two unusual PLAG-1 fusions, involving YWHAZ and EEF1A genes as… read more here.
Keywords: plag1 fusion; eef1a1; lipoblastoma; plag1 ... See more keywords
What is hiding behind S100 protein and SOX10 positive oncocytomas? Oncocytic pleomorphic adenoma and myoepithelioma with novel gene fusions in a subset of cases.
Sign Up to like & getrecommendations! Published in 2020 at "Human pathology"
DOI: 10.1016/j.humpath.2020.07.009
Abstract: Oncocytomas (OC) in salivary glands are rare benign tumors composed of mitochondria-rich epithelial cells (oncocytes), mostly localized in the parotid gland. The treatment of choice is simple excision. Extensive oncocytic metaplasia of pleomorphic adenoma (PA)… read more here.
Keywords: gene fusions; plag1; s100 protein; protein sox10 ... See more keywords
Pleomorphic Adenoma Gene 1 Is Needed For Timely Zygotic Genome Activation and Early Embryo Development
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DOI: 10.1038/s41598-019-44882-0
Abstract: Pleomorphic adenoma gene 1 (PLAG1) is a transcription factor involved in cancer and growth. We discovered a de novo DNA motif containing a PLAG1 binding site in the promoters of genes activated during zygotic genome… read more here.
Keywords: gene; pleomorphic adenoma; activation; plag1 ... See more keywords
Genetic variation in PLAG1 is associated with early fertility in Australian Brahman cattle
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DOI: 10.1093/jas/skac084
Abstract: Abstract Variation in the genome region coding for PLAG1 has well-documented associations with skeletal growth and age at puberty in cattle. However, the influence of PLAG1 on other economically important traits such as cow stayability… read more here.
Keywords: plag1; australian brahman; variation; fertility ... See more keywords
Association of pleomorphic adenoma gene 1 with body weight and measurement of Bali cattle (Bos javanicus)
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DOI: 10.14202/vetworld.2022.782-788
Abstract: Background and Aim: Pleomorphic adenoma gene 1 (PLAG1) encodes a multifunctional transcription factor that controls many genes and pathways and is associated with cattle body weight and measurements. This study aimed to evaluate the association… read more here.
Keywords: plag1; body length; bali cattle; body weight ... See more keywords
PLAG1 g.8795C>T Mutation Regulates Early Body Weight in Hu Sheep by Weakening miR-139 Binding
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DOI: 10.3390/genes14020467
Abstract: Sheep birth and weaning weights indicate their growth and survival. Thus, identifying molecular genetic markers for early body weight is important in sheep breeding. Pleomorphic adenoma gene 1 (PLAG1) is important for regulating birth weight… read more here.
Keywords: plag1; mir 139; 8795c mutation; body weight ... See more keywords
Deficiency of the transcription factor PLAG1 results in aberrant coiling and morphology of the epididymis
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DOI: 10.4103/aja.aja_87_19
Abstract: Mice deficient in the transcription factor pleomorphic adenoma gene 1 (PLAG1) exhibit reproductive issues that are characterized, in part, by decreased progressive sperm motility in the male. However, the underlying cause of this impairment is… read more here.
Keywords: factor; transcription factor; mice; plag1 ... See more keywords