Identification of Plagl1/Zac1 binding sites and target genes establishes its role in the regulation of extracellular matrix genes and the imprinted gene network
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DOI: 10.1093/nar/gkx672
Abstract: Abstract PLAGL1/ZAC1 undergoes parental genomic imprinting, is paternally expressed, and is a member of the imprinted gene network (IGN). It encodes a zinc finger transcription factor with anti-proliferative activity and is a candidate tumor suppressor… read more here.
Keywords: plagl1; target genes; extracellular matrix; gene ... See more keywords
Polycomb protein RYBP activates transcription factor Plagl1 during in vitro cardiac differentiation of mouse embryonic stem cells
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DOI: 10.1098/rsob.220305
Abstract: RING1 and YY1 binding protein (RYBP) is primarily known to function as a repressor being a core component of the non-canonical polycomb repressive complexes 1 (ncPRC1s). However, several ncPRC1-independent functions of RYBP have also been… read more here.
Keywords: protein rybp; embryonic stem; mouse embryonic; plagl1 ... See more keywords