Articles with "plague" as a keyword



Novel Bivalent mRNA‐LNP Vaccine for Highly Effective Protection against Pneumonic Plague

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Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202501286

Abstract: Yersinia pestis, the causative agent of plague, remains a significant global health hazard and a potential top‐tier biothreat despite modern medical advances. Here, two mRNA constructs encoding different versions of the low‐calcium response virulence (LcrV)… read more here.

Keywords: protection; pestis; mrna; pneumonic plague ... See more keywords

Owl Pellet Content Analysis Proves an Effective Technique to Monitor a Population of Threatened Julia Creek Dunnarts (Sminthopsis douglasi) Throughout a Native Rodent Plague

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Published in 2025 at "Ecology and Evolution"

DOI: 10.1002/ece3.70922

Abstract: ABSTRACT Logistical, environmental and temporal considerations can limit the effectiveness of long‐term live trapping for small mammals in remote environments. Owl pellet content analysis offers a low‐cost, non‐invasive alternative to live trapping, as it is… read more here.

Keywords: monitor; analysis; owl pellet; plague ... See more keywords
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Plastic surgery during the COVID-19 pandemic times

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Published in 2020 at "European Journal of Plastic Surgery"

DOI: 10.1007/s00238-020-01685-1

Abstract: Today, we are all living through difficult moments due to a new virus named COVID-19 (coronavirus disease 2019) which has led to a global pandemic. The infection started in China in November 2019 and has… read more here.

Keywords: plastic surgery; plague; spread; world ... See more keywords
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Mussismilia braziliensis White Plague Disease Is Characterized by an Affected Coral Immune System and Dysbiosis

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Published in 2020 at "Microbial Ecology"

DOI: 10.1007/s00248-020-01588-5

Abstract: Infectious diseases are one of the major drivers of coral reef decline worldwide. White plague-like disease (WPL) is a widespread disease with a complex etiology that infects several coral species, including the Brazilian endemic species… read more here.

Keywords: plague; disease; immune system; white plague ... See more keywords

eDNA-based crayfish plague monitoring is superior to conventional trap-based assessments in year-round detection probability

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Published in 2017 at "Hydrobiologia"

DOI: 10.1007/s10750-017-3408-8

Abstract: The crayfish plague disease agent Aphanomyces astaci is a major threat to European crayfish populations, leading to mass extinctions when spores are transmitted into habitats of native species by infected invasive crayfish species. Current methods… read more here.

Keywords: detection; plague; based crayfish; monitoring ... See more keywords

Oral vaccination against plague using Yersinia pseudotuberculosis.

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Published in 2017 at "Chemico-biological interactions"

DOI: 10.1016/j.cbi.2016.03.030

Abstract: Yersinia pestis, the agent of plague, is among the deadliest bacterial pathogens affecting humans, and is a potential biological weapon. Because antibiotic resistant strains of Yersinia pestis have been observed or could be engineered for… read more here.

Keywords: plague; pestis; vaccine; vaccination ... See more keywords

Humoral and cellular immune correlates of protection against bubonic plague by a live Yersinia pseudotuberculosis vaccine.

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Published in 2019 at "Vaccine"

DOI: 10.1016/j.vaccine.2018.11.022

Abstract: Immunization with the live-attenuated Yersinia pseudotuberculosis VTnF1 strain producing a Yersinia pestis F1 pseudocapsule efficiently protects mice against bubonic and pneumonic plague. In clinical trials, demonstration of a plague vaccine's efficacy in humans will not… read more here.

Keywords: protection; correlates protection; plague; humoral cellular ... See more keywords

Robust Th1 cellular and humoral responses generated by the Yersinia pestis rF1-V subunit vaccine formulated to contain an agonist of the CD137 pathway do not translate into increased protection against pneumonic plague.

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Published in 2019 at "Vaccine"

DOI: 10.1016/j.vaccine.2019.07.103

Abstract: Yersinia pestis is the causative agent of plague and is a re-emerging pathogen that also has the potential as a biological weapon, necessitating the development of a preventive vaccine. Despite intense efforts for the last… read more here.

Keywords: protection; plague; th1 cellular; pneumonic plague ... See more keywords
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Single-dose intranasal subunit vaccine rapidly clears secondary sepsis in a high-dose pneumonic plague infection.

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Published in 2021 at "Vaccine"

DOI: 10.1016/j.vaccine.2021.01.040

Abstract: Yersinia pestis, the causative agent of plague, has killed millions throughout human history. Though public health initiatives have reduced the number of plague cases, it remains endemic in many areas of the world. It also… read more here.

Keywords: plague; pestis; tmv; histopathology ... See more keywords

A ‘Suitable Soil’: Plague’s Urban Breeding Grounds at the Dawn of the Third Pandemic

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Published in 2017 at "Medical History"

DOI: 10.1017/mdh.2017.32

Abstract: A pressing question during the first half-decade of the third plague pandemic (1894–9) was what was a ‘suitable soil’ for the disease. The question related to plague’s perceived ability to disappear from a given city… read more here.

Keywords: soil plague; plague; suitable soil; urban breeding ... See more keywords

The Plague of Provence (1720–2) and debates in Britain on the cross-species transmission of disease

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Published in 2025 at "Medical History"

DOI: 10.1017/mdh.2025.10013

Abstract: Abstract While the plague of Provence is the most studied outbreak of the disease in early modern Europe, there is little in the extensive historiography on this topic about fears of the cross-species transmission of… read more here.

Keywords: transmission; disease; plague provence; plague ... See more keywords