Plakoglobin and High-Mobility Group Box 1 Mediate Intestinal Epithelial Cell Apoptosis Induced by Clostridioides difficile TcdB
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DOI: 10.1128/mbio.01849-22
Abstract: Clostridioides difficile infection (CDI) is the leading cause of hospital-acquired diarrhea. Toxins, especially TcdB, cause epithelial cell apoptosis, but the underlying cell death mechanism is less clear. ABSTRACT Clostridioides difficile infection (CDI) is the leading… read more here.
Keywords: cell; apoptosis; epithelial cell; plakoglobin ... See more keywords
Cardiomyocyte adhesion and hyperadhesion differentially require ERK1/2 and plakoglobin
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DOI: 10.1172/jci.insight.140066
Abstract: Arrhythmogenic cardiomyopathy (AC) is a heart disease often caused by mutations in genes coding for desmosomal proteins, including desmoglein-2 (DSG2), plakoglobin (PG), and desmoplakin (DP). Therapy is based on symptoms and limiting arrhythmia, because the… read more here.
Keywords: plakoglobin; adhesion hyperadhesion; cardiomyocyte adhesion; adhesion ... See more keywords
Beyond cell-cell adhesion: Plakoglobin and the regulation of tumorigenesis and metastasis
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DOI: 10.18632/oncotarget.15650
Abstract: Plakoglobin (also known as? -catenin) is a member of the Armadillo family of proteins and a paralog of β -catenin. Plakoglobin is a component of both the adherens junctions and desmosomes, and therefore plays a… read more here.
Keywords: cell cell; tumorigenesis metastasis; plakoglobin; cell adhesion ... See more keywords