An LRR Receptor-Teneurin System Directs Planar Polarity at Compartment Boundaries.
Sign Up to like & getrecommendations! Published in 2019 at "Developmental cell"
DOI: 10.1016/j.devcel.2019.08.003
Abstract: Epithelial cells dynamically self-organize in response to extracellular spatial cues relayed by cell-surface receptors. During convergent extension in Drosophila, Toll-related receptors direct planar polarized cell rearrangements that elongate the head-to-tail axis. However, many cells establish… read more here.
Keywords: planar polarity; tartan ten; polarity; receptor ... See more keywords
New insights into regulation and function of planar polarity in the inner ear
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.134373
Abstract: Acquisition of cell polarity generates signaling and cytoskeletal asymmetry and thus underpins polarized cell behaviors during tissue morphogenesis. In epithelial tissues, both apical basal polarity and planar polarity, which refers to cell polarization along an… read more here.
Keywords: planar polarity; insights regulation; polarity; new insights ... See more keywords
Tissue shear as a cue for aligning planar polarity in the developing Drosophila wing
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-56744-7
Abstract: Planar polarity establishment in epithelia requires interpretation of directional tissue-level information at cellular and molecular levels. Mechanical forces exerted during tissue morphogenesis are emerging as crucial tissue-level directional cues, yet the mechanisms by which they… read more here.
Keywords: cell; tissue stress; polarity; planar polarity ... See more keywords
Planar polarity in primate cone photoreceptors: a potential role in Stiles Crawford effect phototropism
Sign Up to like & getrecommendations! Published in 2022 at "Communications Biology"
DOI: 10.1038/s42003-021-02998-y
Abstract: Human cone phototropism is a key mechanism underlying the Stiles-Crawford effect, a psychophysiological phenomenon according to which photoreceptor outer/inner segments are aligned along with the direction of incoming light. However, such photomechanical movements of photoreceptors… read more here.
Keywords: microscopy; stiles crawford; planar polarity; crawford effect ... See more keywords
Characterisation of cell-scale signalling by the core planar polarity pathway during Drosophila wing development
Sign Up to like & getrecommendations! Published in 2025 at "eLife"
DOI: 10.1101/2024.10.14.618159
Abstract: In developing epithelia, cells become planar polarised through asymmetric localisation of the core planar polarity proteins to opposite cell membranes, where they form stable intercellular complexes. Current models differ regarding the signalling mechanisms required for… read more here.
Keywords: cell; core; planar polarity; cell scale ... See more keywords
The Planar Polarity Component VANGL2 Is a Key Regulator of Mechanosignaling
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.577201
Abstract: VANGL2 is a component of the planar cell polarity (PCP) pathway, which regulates tissue polarity and patterning. The Vangl2Lp mutation causes lung branching defects due to dysfunctional actomyosin-driven morphogenesis. Since the actomyosin network regulates cell… read more here.
Keywords: planar polarity; vangl2; polarity component; component vangl2 ... See more keywords
Cytoskeletal Control of Planar Polarity in Root Hair Development
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2020.580935
Abstract: Polarity is at the core of plant development, as well as that of other multicellular organisms since polarization acts as a driving force to generate a variety of specialized cells. Therefore, unraveling how cells establish… read more here.
Keywords: planar polarity; control planar; hair; polarity ... See more keywords