Chemical Modification of Plant Alkaloids. 8. Stereocontrolled T-Reactions of (1R,5S,12S)-Tetrahydrocytisine Derivatives
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DOI: 10.1007/s10600-018-2459-z
Abstract: New heterocyclic quinolizidine systems were prepared from (1R,5S,12S)-tetrahydrocytisine. The synthetic scheme included arylation of tetrahydrocytisine by 2-fluoro-5-nitrobenzaldehyde and condensation of the resulting aldehyde with 1,3-dimethylbarbituric acid. The Knoevenagel intermediate obtained from the condensation was cyclized… read more here.
Keywords: 12s tetrahydrocytisine; plant alkaloids; tetrahydrocytisine; alkaloids stereocontrolled ... See more keywords
Evaluation of the Anticancer Activities of the Plant Alkaloids Sanguinarine and Chelerythrine in Human Breast Adenocarcinoma Cells.
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DOI: 10.2174/1871520617666170213115132
Abstract: BACKGROUND Breast cancer is associated with a high mortality rate around the world due to its aggressiveness and high resistance to conventional therapies. Sanguinarine (SAN) and Chelerythrine (CHE) are plant alkaloids extracted from Sanguinaria canadensis… read more here.
Keywords: anticancer activities; plant alkaloids; breast; che ... See more keywords