Discovery of an H3K36me3-Derived Peptidomimetic Ligand with Enhanced Affinity for Plant Homeodomain Finger Protein 1 (PHF1).
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c00430
Abstract: Plant homeodomain finger protein 1 (PHF1) is an accessory component of the gene silencing complex polycomb repressive complex 2 and recognizes the active chromatin mark, trimethylated lysine 36 of histone H3 (H3K36me3). In addition to… read more here.
Keywords: plant homeodomain; protein phf1; homeodomain finger; finger protein ... See more keywords
Design of a Chemical Probe for the Bromodomain and Plant Homeodomain Finger-Containing (BRPF) Family of Proteins.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.7b00611
Abstract: The bromodomain and plant homeodomain finger-containing (BRPF) family are scaffolding proteins important for the recruitment of histone acetyltransferases of the MYST family to chromatin. Here, we describe NI-57 (16) as new pan-BRPF chemical probe of… read more here.
Keywords: plant homeodomain; finger containing; bromodomain plant; family ... See more keywords
Plant homeodomain finger protein 6 in the regulation of normal and malignant hematopoiesis.
Sign Up to like & getrecommendations! Published in 2020 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000588
Abstract: PURPOSE OF REVIEW Even though an increasing amount of sequencing data on the leukemia genome has highlighted a tumor-suppressive function for plant homeodomain finger protein 6 (PHF6), its role in the hematopoietic system remained elusive… read more here.
Keywords: phf6; homeodomain finger; plant homeodomain; finger protein ... See more keywords
MALE STERILITY 3 encodes a plant homeodomain‐finger protein for male fertility in soybean
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Integrative Plant Biology"
DOI: 10.1111/jipb.13242
Abstract: Abstract Male‐sterile plants are used in hybrid breeding to improve yield in soybean (Glycine max (L.) Merr.). Developing the capability to alter fertility under different environmental conditions could broaden germplasm resources and simplify hybrid production.… read more here.
Keywords: plant homeodomain; male sterility; fertility; ms3 ... See more keywords
A comprehensive pan-cancer analysis unveiling the oncogenic effect of plant homeodomain finger protein 14 (PHF14) in human tumors
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2023.1073138
Abstract: The plant homeodomain (PHD) finger refers to a protein motif that plays a key role in the recognition and translation of histone modification marks by promoting gene transcriptional activation and silencing. As an important member… read more here.
Keywords: pan cancer; analysis; cancer; plant homeodomain ... See more keywords