Absence of the Vitamin D Receptor Inhibits Atherosclerotic Plaque Calcification in Female Hypercholesterolemic Mice
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DOI: 10.1002/jcb.25679
Abstract: Epidemiological and clinical data suggest adverse cardiovascular outcomes with respect to vitamin D deficiency. Here, we explored the effects of vitamin D in atherosclerotic plaque calcification in vivo by utilizing vitamin D receptor (Vdr)‐deficient mice… read more here.
Keywords: vdr; calcification; mice; plaque calcification ... See more keywords
Matrix metalloproteinase-10 deficiency delays atherosclerosis progression and plaque calcification.
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DOI: 10.1016/j.atherosclerosis.2018.09.022
Abstract: BACKGROUND AND AIMS Matrix metalloproteinases (MMPs) have been implicated in atherosclerosis and vascular calcification. Among them, we reported that MMP10 is present in human atheroma, associated with atherosclerosis. However, it remains unclear whether MMP10 is… read more here.
Keywords: calcification; mmp10; mice; plaque calcification ... See more keywords
Osteomodulin Gene Expression Is Associated With Plaque Calcification, Stability, and Fewer Cardiovascular Events in the CPIP Cohort
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DOI: 10.1161/strokeaha.121.037223
Abstract: Supplemental Digital Content is available in the text. Background: Stable atherosclerotic plaques are characterized by thick fibrous caps of smooth muscle cells, collagen, and macrocalcifications. Identifying factors of plaque stability is necessary to design drugs… read more here.
Keywords: associated plaque; calcification; expression; plaque calcification ... See more keywords