IL-1β-driven amyloid plaque clearance is associated with an expansion of transcriptionally reprogrammed microglia
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DOI: 10.1186/s12974-019-1645-7
Abstract: BackgroundNeuroinflammation is thought to contribute to the pathogenesis of Alzheimer’s disease (AD), yet numerous studies have demonstrated a beneficial role for neuroinflammation in amyloid plaque clearance. We have previously shown that sustained expression of IL-1β… read more here.
Keywords: plaque clearance; ps1 mice; clearance; amyloid plaque ... See more keywords