Trehalose Inhibits Aβ Generation and Plaque Formation in Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Neurobiology"
DOI: 10.1007/s12035-020-01942-1
Abstract: Alzheimer’s disease (AD) is the most common neurodegenerative disease, and there has been no disease-modifying treatment for AD. Recent studies suggest that trehalose may have beneficial effect on neurodegenerative diseases through regulating autophagy and facilitating… read more here.
Keywords: generation; alzheimer disease; plaque formation; disease ... See more keywords
Bifurcation analysis of a free boundary model of the atherosclerotic plaque formation associated with the cholesterol ratio.
Sign Up to like & getrecommendations! Published in 2020 at "Chaos"
DOI: 10.1063/5.0009121
Abstract: The low-density lipoprotein (LDL)/high-density lipoprotein (HDL)-cholesterol ratio has been shown to have a high correlation with the cardiovascular risk assessment. Is it possible to quantify the correlation mathematically? In this paper, we develop a bifurcation… read more here.
Keywords: bifurcation analysis; analysis; free boundary; plaque formation ... See more keywords
Fe-Mn Plaque Formation Mechanism Underlying the Inhibition of Cadmium Absorption by Rice Under Oxygation Conditions.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental engineering science"
DOI: 10.1089/ees.2020.0434
Abstract: Oxygation (O) is a water-saving and energy-saving irrigation method that can also influence the absorption of cadmium (Cd) by rice, but the related mechanism is still unclear. In this study, the relationship between O method… read more here.
Keywords: absorption rice; rice; plaque formation;
Mild Hyperhomocysteinemia Induced by a Hypomethylating Diet Does Not Favor Aortic Plaque Formation in apoE Knockout Mice (P24-037-19).
Sign Up to like & getrecommendations! Published in 2019 at "Current developments in nutrition"
DOI: 10.1093/cdn/nzz044.p24-037-19
Abstract: Objectives Hyperhomocysteinemia is an independent risk factor for atherosclerosis and cardiovascular disease through mechanisms still incompletely defined. We investigated the impact of mild diet-induced accumulation of homocysteine on atherosclerotic plaque formation in apoE knockout (KO)… read more here.
Keywords: mice; plaque; hyperhomocysteinemia; apoe ... See more keywords
IDDF2019-ABS-0081 Portal free cholesterol and oxidized-LDL accumulation is associated with plaque formation and inflammation in human NAFLD
Sign Up to like & getrecommendations! Published in 2019 at "Gut"
DOI: 10.1136/gutjnl-2019-iddfabstracts.88
Abstract: Background Macrophage uptake of oxidized low-density lipoprotein (oxLDL) which may result in the accumulation of free cholesterol and subsequent crystal formation that can induce NLRP3 inflammasome activation. Hepatic free cholesterol content is significantly increased in… read more here.
Keywords: free cholesterol; cholesterol; accumulation; plaque formation ... See more keywords
Preventing Cholesterol-Induced Perk (Protein Kinase RNA-Like Endoplasmic Reticulum Kinase) Signaling in Smooth Muscle Cells Blocks Atherosclerotic Plaque Formation
Sign Up to like & getrecommendations! Published in 2022 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.121.317451
Abstract: Background: Vascular smooth muscle cells (SMCs) undergo complex phenotypic modulation with atherosclerotic plaque formation in hyperlipidemic mice, which is characterized by de-differentiation and heterogeneous increases in the expression of macrophage, fibroblast, osteogenic, and stem cell… read more here.
Keywords: endoplasmic reticulum; atherosclerotic plaque; cholesterol; plaque formation ... See more keywords
Genomic loss in environmental and isogenic morphotype isolates of Burkholderia pseudomallei is associated with intracellular survival and plaque-forming efficiency
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0008590
Abstract: Background Burkholderia pseudomallei is an environmental bacterium that causes melioidosis. A facultative intracellular pathogen, B. pseudomallei can induce multinucleated giant cells (MNGCs) leading to plaque formation in vitro. B. pseudomallei can switch colony morphotypes under… read more here.
Keywords: morphotype; formation; plaque; plaque formation ... See more keywords
Sodium thiocyanate treatment attenuates atherosclerotic plaque formation and improves endothelial regeneration in mice
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0214476
Abstract: Introduction Atherosclerotic plaque formation is an inflammatory process that involves the recruitment of neutrophil granulocytes and the generation of reactive oxygen species (ROS). ROS formation by myeloperoxidase, a key enzyme in H2O2 degradation, can be… read more here.
Keywords: treatment; formation; mice; plaque ... See more keywords
Effects of atherogenic diet supplemented with fermentable carbohydrates on metabolic responses and plaque formation in coronary arteries using a Saddleback pig model
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0275214
Abstract: Fermentable carbohydrates are gaining interest in the field of human nutrition because of their benefits in obesity-related comorbidities. The aim of this study was to investigate the influence of fermentable carbohydrates, such as pectin and… read more here.
Keywords: fermentable carbohydrates; plaque formation; atherogenic diet; coronary arteries ... See more keywords
Microglia-Derived Interleukin 23: A Crucial Cytokine in Alzheimer's Disease?
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2021.639353
Abstract: Neuronal cell death, amyloid β plaque formation and development of neurofibrillary tangles are among the characteristics of Alzheimer's disease (AD). In addition to neurodegeneration, inflammatory processes such as activation of microglia and astrocytes are crucial… read more here.
Keywords: alzheimer disease; microglia derived; derived interleukin; disease ... See more keywords
Strategies to Combat Caries by Maintaining the Integrity of Biofilm and Homeostasis during the Rapid Phase of Supragingival Plaque Formation
Sign Up to like & getrecommendations! Published in 2022 at "Antibiotics"
DOI: 10.3390/antibiotics11070880
Abstract: Bacteria in the oral cavity, including commensals and opportunistic pathogens, are organized into highly specialized sessile communities, coexisting in homeostasis with the host under healthy conditions. A dysbiotic environment during biofilm evolution, however, allows opportunistic… read more here.
Keywords: rapid phase; plaque formation; biofilm; integrity ... See more keywords