The effect of Bruton's tyrosine kinase inhibitor ibrutinib on atherothrombus formation under stenotic flow conditions.
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DOI: 10.1016/j.thromres.2022.02.020
Abstract: BACKGROUND Bruton's kinase (Btk) is critical for collagen-triggered platelet signal transduction. The Btk inhibitor ibrutinib has been shown to selectively block platelet adhesion to atherosclerotic plaque material under laminar arterial flow. However, this has not… read more here.
Keywords: inhibitor ibrutinib; plaque material; collagen; ibrutinib ... See more keywords